Colored Pain Drawing as a Clinical Tool in Differentiating Neuropathic Pain from Non-Neuropathic Pain.

Pain Medicine : the Official Journal of the American Academy of Pain Medicine
Nalini SehgalMiroslav Misha Backonja

Abstract

This is a prospective, blinded, case-control study of patients with chronic pain using body diagrams and colored markers to show the distribution and quality of pain and sensory symptoms (aching, burning, tingling, numbness, and sensitivity to touch) experienced in affected body parts. Two pain physicians, blinded to patients' clinical diagnoses, independently reviewed and classified each colored pain drawing (CPD) for presence of neuropathic pain (NeuP) vs. non-neuropathic pain (NoP). A clinical diagnosis (gold standard) of NeuP was made in 151 of 213 (70.9%) enrolled patients. CPD assessment at "first glance" by both examiners resulted in correctly categorizing 137 (64.3% by examiner 1) and 156 (73.2% by examiner 2) CPDs. Next, classification of CPDs by both physicians, using predefined criteria of spatial distribution and quality of pain-sensory symptoms, improved concordance to 212 of 213 CPDs (Kappa = 0.99). The diagnostic ability to correctly identify NeuP and NoP by both examiners increased to 171 (80.2%) CPDs, with 80.1% sensitivity and 80.6% specificity (Kappa = 0.56 [95% confidence interval: 0.44-0.68]). The severity scores for pain and sensory symptoms (burning, tingling, numbness, and sensitivity to touch) on the Ne...Continue Reading

References

Sep 1, 1992·Journal of Spinal Disorders·N H MannI Enger
Jan 1, 1992·Scandinavian Journal of Plastic and Reconstructive Surgery and Hand Surgery·M ArnerJ Holmberg
Jan 1, 1986·Pain·R B MargolisS J Krause
Apr 1, 1988·Spine·A UdénH Bergenudd
Apr 1, 1988·Pain·R B MargolisR C Tait
Oct 1, 1983·Journal of Personality Assessment·N V RamanaiahT Schill
Jan 1, 1995·International Orthopaedics·K Takata, H Hirotani
Oct 1, 1996·Acta Orthopaedica Scandinavica·H BrismarO Svensson
May 20, 1999·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·D D OhnmeissJ Ekholm
Oct 19, 1999·The Clinical Journal of Pain·D D OhnmeissJ Ekholm
Sep 11, 2003·The Clinical Journal of Pain·Steven J Krause, Misha-Miroslav Backonja
Sep 1, 2004·The Journal of Pain : Official Journal of the American Pain Society·Roland StaudCharles J Vierck
Nov 24, 2004·The Journal of Pain : Official Journal of the American Pain Society·Robert N JamisonJohn C Baird
Apr 1, 2005·Journal of Spinal Disorders & Techniques·Ketan C PandeRohit Kanoi
Jun 15, 2006·The Clinical Journal of Pain·Dawn CarnesMartin Underwood
Feb 20, 2007·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Bo BertilsonLars-Erik Strender
Apr 22, 2009·Journal of Psychosomatic Research·Elizabeth BroadbentLisa Reynolds
Apr 28, 2010·The Spine Journal : Official Journal of the North American Spine Society·Thomas AndersenCody Bünger
Aug 14, 2012·Pediatric Pulmonology·Gabriel Xavier-SouzaUNKNOWN PNEUMOPAC-Efficacy Study Group
Dec 22, 2012·BMC Musculoskeletal Disorders·Niklaus EgloffMarie-Louise Gander Ferrari
Dec 30, 2014·AJR. American Journal of Roentgenology·Andrew S PhelpsJohn D MacKenzie
Mar 11, 2015·The Clinical Journal of Pain·Shellie A BoudreauLine L Egsgaard
Aug 20, 2016·Family Practice·Erik PoulsenJan Hartvigsen
Nov 8, 2016·The Journal of Orthopaedic and Sports Physical Therapy·Daniel I RhonSteven Z George
Jul 19, 2017·Upsala Journal of Medical Sciences·Anna MacDowallClaes Olerud
Dec 13, 2017·Journal of Applied Biobehavioral Research·Lisa H TrahanDiane M Novy
Apr 17, 2018·Physiotherapy Theory and Practice·Felipe ReisTimothy Wideman
Sep 7, 2019·JMIR MHealth and UHealth·Nour ShaballoutFlorian Beissner
Oct 31, 2019·Pain Practice : the Official Journal of World Institute of Pain·Matthew J WillettDeborah Falla

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.