Colostomy for Perianal Sepsis With Ecthyma Gangrenosum in Immunocompromised Children

Journal of Pediatric Hematology/oncology
Raphael N Vuille-Dit-BilleMichael A Grotzer

Abstract

Perianal sepsis with ecthyma gangrenosum is a severe and potentially mutilating complication in immunocompromised children. Therapies include antimicrobial treatment, incision and drainage, generous tissue debridement, and skin transplantation. We describe 3 children with acute lymphoblastic leukemia having sepsis with Pseudomonas aeruginosa in febrile neutropenia and severe perianal infections treated relatively early with a protective colostomy. Indications for colostomy were nonhealing wounds, and ceaseless pain. All patients showed a rapid reduction of pain. Complete wound healing was seen in 2 patients, and considerable pain reduction and increased quality of life were seen in a third patient during palliative care. These results suggest that a protective colostomy should be considered early in the management of immunocompromised children with ecthyma gangrenosum.

References

Nov 24, 1999·Burns : Journal of the International Society for Burn Injuries·C J QuarmbyH Rode
Mar 29, 2006·Journal of Pediatric Surgery·Alberto PenaMarc A Levitt
Jul 31, 2007·International Journal of Surgery·S O EkenzeC C Amah

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Citations

May 16, 2020·Gastroenterology Research and Practice·Bradley WallaceRaphael N Vuille-Dit-Bille
Nov 16, 2020·Urology·Mellissa DelcontRaphael N Vuille-Dit-Bille
May 13, 2021·Advances in Skin & Wound Care·Emrah GünErdal İnce

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Methods Mentioned

BETA
blood drawn
lavages

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