Coma in a 20-month-old child from an ingestion of a toy containing 1,4-butanediol, a precursor of gamma-hydroxybutyrate

Pediatric Emergency Care
Laura A OrtmannSteve M Schexnayder

Abstract

Ingestion of plastic toys is common in children and usually does not result in harm. We report a case of coma in a 20-month-old child after an ingestion of a toy containing 1,4-butanediol, an industrial solvent used to manufacture plastics. When ingested, 1,4-butanediol is metabolized to gamma-hydroxybutyrate, which can have significant systemic effects including death. Health care providers should suspect the possibility of a toxic component when a presumed nontoxic object causes unusual symptoms.

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Citations

Jul 4, 2012·Clinical Toxicology : the Official Journal of the American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists·Leo J SchepBruno Mégarbane
Mar 26, 2016·Clinical Case Reports·Victoria Elizabeth de KnegtMalene Landbo Børresen
Oct 12, 2018·Clinical Toxicology : the Official Journal of the American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists·Francesco Paolo Busardò, Alan Wayne Jones
Jul 1, 2020·Arhiv za higijenu rada i toksikologiju·Enrico MarinelliSimona Zaami

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