Comb-push ultrasound shear elastography of breast masses: initial results show promise

PloS One
Max DenisAzra Alizad

Abstract

To evaluate the performance of Comb-push Ultrasound Shear Elastography (CUSE) for classification of breast masses. CUSE is an ultrasound-based quantitative two-dimensional shear wave elasticity imaging technique, which utilizes multiple laterally distributed acoustic radiation force (ARF) beams to simultaneously excite the tissue and induce shear waves. Female patients who were categorized as having suspicious breast masses underwent CUSE evaluations prior to biopsy. An elasticity estimate within the breast mass was obtained from the CUSE shear wave speed map. Elasticity estimates of various types of benign and malignant masses were compared with biopsy results. Fifty-four female patients with suspicious breast masses from our ongoing study are presented. Our cohort included 31 malignant and 23 benign breast masses. Our results indicate that the mean shear wave speed was significantly higher in malignant masses (6 ± 1.58 m/s) in comparison to benign masses (3.65 ± 1.36 m/s). Therefore, the stiffness of the mass quantified by the Young's modulus is significantly higher in malignant masses. According to the receiver operating characteristic curve (ROC), the optimal cut-off value of 83 kPa yields 87.10% sensitivity, 82.61% specifi...Continue Reading

References

Aug 26, 1998·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·W Teh, A R Wilson
Apr 10, 1999·Ultrasonic Imaging·T A KrouskopT Hall
Jul 1, 1999·Ultrasound in Medicine & Biology·A P SarvazyanS Y Emelianov
Dec 2, 1999·Radiology·G RahbarL W Bassett
Nov 5, 2003·Ultrasound in Medicine & Biology·J BercoffM Meunier
Feb 11, 2004·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·S-C ChenS Hsueh
Feb 13, 2004·Ultraschall in der Medizin : Organ der Deutschen Gesellschaft für Ultraschall in der Medizin, [der] Österreichischen Gesellschaft für Ultraschall in der Medizin, [der] Schweizerischen Gesellschaft für Ultraschall in Medizin und Biologie·R OhlingerG Köhler
May 14, 2004·IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control·Jérémy BercoffMathias Fink
Dec 7, 2006·Radiologic Clinics of North America·Raj Mohan Paspulati, Shweta Bhatt
Oct 18, 2007·Radiology·Elizabeth S BurnsideNicholas J Hangiandreou
Feb 6, 2008·The Journal of the Acoustical Society of America·J-L GennissonM Fink
May 15, 2008·JAMA : the Journal of the American Medical Association·Wendie A BergUNKNOWN ACRIN 6666 Investigators
May 5, 2009·IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control·Gabriel MontaldoMathias Fink
May 28, 2010·Radiology·Alexandra AthanasiouSylvia Neuenschwander
Dec 3, 2010·Breast Cancer Research : BCR·Andrew EvansAlastair Thompson
Jan 8, 2011·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Vittorio CorsettiStefano Ciatto
Feb 19, 2011·Radiology·Jung Min ChangSeung Ja Kim
Jun 18, 2011·Breast Cancer Research and Treatment·Jung Min ChangSeung Ja Kim
Jan 3, 2012·European Radiology·David O CosgroveUNKNOWN BE1 Study Group
Feb 3, 2012·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Min BaiXiao Jia
Feb 7, 2012·Current Medical Imaging Reviews·Armen SarvazyanBrian S Garra
Apr 5, 2012·JAMA : the Journal of the American Medical Association·Wendie A BergUNKNOWN ACRIN 6666 Investigators
May 2, 2012·IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control·Heldmuth Latorre-OssaMickaël Tanter
May 31, 2012·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Richard G Barr, Zheng Zhang
Apr 18, 2013·IEEE Transactions on Medical Imaging·Pengfei SongShigao Chen
Apr 24, 2013·Diagnostic and Interventional Imaging·J-M CorreasO Hélénon
Mar 8, 2014·European Journal of Radiology·Victor IanculescuCorinne Balleyguier
Mar 13, 2014·Ultrasound in Medicine & Biology·Pengfei SongShigao Chen
May 7, 2014·BioMed Research International·Minghua YaoHuixiong Xu
Aug 15, 2014·IEEE Transactions on Medical Imaging·Mohammad MehrmohammadiAzra Alizad

❮ Previous
Next ❯

Citations

Apr 18, 2017·Proceedings. Mathematical, Physical, and Engineering Sciences·Guo-Yang Li, Yanping Cao
May 10, 2017·International Journal of Computer Assisted Radiology and Surgery·Katrin SkerlAndrew Evans
Sep 19, 2020·Scientific Reports·Niloufar SaharkhizElisa E Konofagou
Jun 19, 2021·Physics in Medicine and Biology·Reza Khodayi-MehrWilkins Aquino
Nov 15, 2020·The Breast : Official Journal of the European Society of Mastology·Juanjuan GuAzra Alizad
Mar 6, 2018··Mark A. AnastasioSuhail S. Alshahrani

❮ Previous
Next ❯

Methods Mentioned

BETA
biopsies
imaging technique
biopsy
imaging

Software Mentioned

Matlab
CUSE
FCUSE

Related Concepts

Related Feeds

Cancer Imaging

Imaging techniques, including CT and MR, have become essential to tumor detection, diagnosis, and monitoring. Here is the latest research on cancer imaging.

Breast Invasive Carcinoma

Invasive breast cancers indicate a spread into breast tissues and lymph nodes. Here are the latest discoveries pertaining to breast invasive carcinomas.

Carcinoma, Ductal

Ductal carcinoma is a malignant neoplasm involving the ductal systems of any of a number of organs, such as the mammary glands, pancreas, prostate or lacrimal gland. Discover the latest research on ductal carcinoma here.

Breast Invasive Carcinoma (Keystone)

Invasive breast cancers indicate a spread into breast tissues and lymph nodes. Here are the latest discoveries pertaining to breast invasive carcinomas.