Combination antibiotic therapy for the treatment of infective endocarditis due to enterococci

Infection
Sebastiano LeoneSilvano Esposito

Abstract

Enterococci are common causes of infective endocarditis (IE) in both health care and community-based setting. Enterococcal IE requires bactericidal therapy for an optimal outcome. For decades, cell-wall-active antimicrobial agents (penicillins or vancomycin) in combination with aminoglycosides were the cornerstone of the treatment; however, the emergence of antibiotic resistance has significantly reduced the efficacy of these regimens. Data for this review were identified by searches of MEDLINE and references from relevant articles on antibiotic combination regimens for the treatment of enterococcal IE. Abstracts presented in scientific conferences were not searched for. New effective and safe combination treatments, including double-β-lactam and daptomycin/β-lactam combination, are proving useful for the management of IE due to enterococci.

References

Jan 1, 1990·Clinical Microbiology Reviews·B E Murray
Jun 1, 1988·Antimicrobial Agents and Chemotherapy·L M BushD Kaye
Sep 1, 1995·Antimicrobial Agents and Chemotherapy·J L MainardiF W Goldstein
Oct 24, 1997·The Journal of Antimicrobial Chemotherapy·M VendittiP Serra
Sep 15, 2000·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·J W Chow
Oct 19, 2000·Antimicrobial Agents and Chemotherapy·T M MurphyW J Weiss
Dec 12, 2001·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Lars OlaisonUNKNOWN Swedish Society of Infectious Diseases Quality Assurance Study Group for Endocarditis
Jan 11, 2003·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Mary C BirminghamJerome J Schentag
Jul 29, 2003·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·S M ZimmerJ Somani
Jul 27, 2004·Antimicrobial Agents and Chemotherapy·Louis B RiceLaurent Gutmann
Oct 21, 2004·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Robert W FinbergMichael J Rybak
Nov 3, 2004·International Journal of Antimicrobial Agents·S EspositoUNKNOWN International OPAT Registry
Jun 28, 2005·Antimicrobial Agents and Chemotherapy·Seiji OnoTetsuro Matsumoto
Sep 16, 2005·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Michael P Stevens, Michael B Edmond
Nov 24, 2005·Antimicrobial Agents and Chemotherapy·George PankeyNalini Patel
Aug 18, 2006·The New England Journal of Medicine·Vance G FowlerUNKNOWN S. aureus Endocarditis and Bacteremia Study Group
Mar 10, 2007·International Journal of Antimicrobial Agents·Silvano Esposito, Sebastiano Leone
Apr 18, 2007·Annals of Internal Medicine·Joan GavaldàAlbert Pahissa
Oct 31, 2007·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Cesar A AriasBarbara E Murray
Jan 18, 2008·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Marianne BilleterChanga Kurukularatne
Oct 14, 2008·Expert Review of Anti-infective Therapy·Cesar A Arias, Barbara E Murray
Mar 11, 2009·Archives of Internal Medicine·David R MurdochUNKNOWN International Collaboration on Endocarditis-Prospective Cohort Study (ICE-PCS) Investigators
Jul 22, 2009·Antimicrobial Agents and Chemotherapy·J M MiróUNKNOWN Hospital Clinic Experimental Endocarditis Study Group
Nov 17, 2009·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Louis D SaravolatzLeonard B Johnson
Jun 24, 2010·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·C A AriasB E Murray
Mar 23, 2011·International Journal of Antimicrobial Agents·Carlos CerveraJose M Miró
Nov 17, 2011·The Journal of Antimicrobial Chemotherapy·F Kate Gould Working Party of the British Society for Antimicrobial Chemotherapy

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Citations

Feb 15, 2019·Current Medical Research and Opinion·Sebastiano LeoneMarco Fiore
May 21, 2019·Expert Review of Gastroenterology & Hepatology·Marco FioreSebastiano Leone
Oct 20, 2020·Expert Review of Cardiovascular Therapy·Christopher J AllenSimon R Redwood

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Aminoglycoside is a medicinal and bacteriologic category of traditional Gram-negative antibacterial medications that inhibit protein synthesis and contain as a portion of the molecule an amino-modified glycoside. Discover the latest research on aminoglycoside here.

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Antimicrobial Resistance

Antimicrobial resistance poses a significant threat to the continued successful use of antimicrobial agents for the treatment of bacterial infections.

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