PMID: 2509339Jan 1, 1989Paper

Combination chemotherapy in inoperable lung cancer--a trial of 2 regimens

The Indian Journal of Chest Diseases & Allied Sciences
D Behera, S K Malik

Abstract

Combination chemotherapy with 3 drugs (vincristine + cyclo-phosphamide + methotrexate of adriamycin) were administered to 36 cases of advanced bronchogenic carcinoma. The median survival for patients with small cell carcinoma (SCC) was 24.5 weeks whereas that for non small cell carcinoma was 27.5 weeks (P greater than 0.05). Fifty-five per cent of the patients survived beyond 6 months; 30.5 per cent survived beyond 1 year and 11 per cent of the patients survived beyond two years. Adriamycin did not prove more effective than methotrexate. However, omission of adriamycin from the regimen may reduce the cost of chemotherapy.

Related Concepts

Related Feeds

Carcinoma, Bronchogenic

Bronchogenic Carcinoma is a malignant lung cancer arising in the epithelium of the bronchus or bronchiole. Discover the latest research on Bronchogenic Carcinoma here.