Combination curettage and modified ALA-PDT for multiple basal cell carcinomas of the face and head.

Photodiagnosis and Photodynamic Therapy
Caihe LiaoXiuli Wang

Abstract

Basal cell carcinoma (BCC) is a common non-melanoma skin malignancy arising in sun exposure area. Patients with multiple BCCs have a high-risk factor for recurrence and are very difficult to  treat with current methods. 5-aminolaevulinic acid-photodynamic therapy (ALA-PDT) treat superficial type of BCCs with superior efficacy and an excellent cosmetic result, but deep tumor success is limited. Herein, a case of numerous nodular BCCs scattered on the face and head, which was treated with the combination of topical curettage and modified ALA-PDT is reported. Curettage was to rapidly scalp away nodular tumors and contributed to ALA transdermal depth to the tumor base. Modified ALA-PDT as an advanced treatment was nearly painless and can cure multiple BCCs of face and head combing curettage.

References

Dec 24, 2005·The Journal of Investigative Dermatology·Even Angell-PetersenKarl-Erik Giercksky
Oct 31, 2015·International Journal of Molecular Sciences·Silvia Rocío LucenaYolanda Gilaberte
May 11, 2016·Journal of the National Comprehensive Cancer Network : JNCCN·Christopher K BichakjianAnita Engh
Sep 16, 2019·Photodiagnosis and Photodynamic Therapy·Duling CaoShuang Zhao

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Basal cell carcinoma is a form of malignant skin cancer found on the head and neck regions and has low rates of metastasis. Discover the latest research on basal cell carcinoma here.