Abstract
Pseudomonal scleritis is a serious and potentially blinding infection that usually is resistant to medical management. Results for three patients with pseudomonal scleritis who were treated with both topical anti-infectives and a combination of intravenous ceftazidime and aminoglycoside are presented in this case series. All three patients had a rapid response to the addition of combination intravenous drug therapy to topical therapy; eradication of the infection and healing of the ocular surface occurred within 8 weeks. Only one patient, in whom cystoid macular edema developed, lost useful vision as a result of the infection. Combination therapy with intravenous ceftazidime and aminoglycoside may be more effective than single-intravenous agents when used in addition to topical antibiotics and may obviate the need for adjunctive surgical procedures, such ascryotherapy, surgical extirpation, or conjunctival recession.
References
Sep 1, 1979·Archives of Ophthalmology·R A Eiferman
Jan 1, 1978·American Journal of Ophthalmology·F P FurgiueleJ G Baron
Nov 1, 1992·Ophthalmology·R S RubinfeldM G Speaker
Nov 15, 1991·American Journal of Ophthalmology·M G Reynolds, E Alfonso
Jul 1, 1985·Antimicrobial Agents and Chemotherapy·J BlaserS H Zinner
Apr 1, 1974·American Journal of Ophthalmology·W A MacIlwaineG L Mandell
Jun 1, 1984·Archives of Ophthalmology·J L AxelrodL Youngworth
Jan 1, 1983·Scandinavian Journal of Infectious Diseases·A M HeilesenN Høiby
May 1, 1980·Antimicrobial Agents and Chemotherapy·R WiseK A Bedford
Jun 1, 1981·American Journal of Ophthalmology·F CodèreW B Jackson
May 1, 1980·Antimicrobial Agents and Chemotherapy·L Verbist, J Verhaegen
Sep 1, 1981·American Journal of Ophthalmology·I M RaberV B Bernardino
Sep 1, 1980·The British Journal of Ophthalmology·K H Tarr, I J Constable
Citations
Dec 21, 2006·Japanese Journal of Ophthalmology·Wataru SaitoShigeaki Ohno
Aug 14, 2009·American Journal of Ophthalmology·Pooja V BhatC Stephen Foster
Aug 25, 2004·Survey of Ophthalmology·Paris G TranosCarlos E Pavesio
Feb 7, 2001·Eye·R RadfordA B Tullo
Jan 13, 2000·Cornea·F C HuangS H Tseng
Mar 28, 2002·Cornea·David Hui-Kang MaRay Jui-Fang Tsai
Sep 15, 2005·Cornea·Kamal FahimShahzad I Mian
Dec 7, 2005·Cornea·Jayter Silva PaulaAntonio Augusto Velasco Cruz
Sep 3, 2009·Cornea·Marta Moreno HonradoJosé A Buil
Dec 22, 2010·Cornea·Hsin-Chiung LinChing-Hsi Hsiao
Jun 23, 2011·Cornea·Matthew A CunninghamKirk R Wilhemus
Jan 1, 2010·BMJ Case Reports·Deric De Wit, Douglas Newman
Aug 6, 1999·The British Journal of Ophthalmology·S O SykesE T Cunningham
Feb 16, 2013·Survey of Ophthalmology·Rishi R DoshiEmmett T Cunningham
Jun 22, 2005·Survey of Ophthalmology·Narciss OkhraviSusan Lightman
Dec 14, 2011·International Journal of Inflammation·Srikant Kumar SahuKalyani Sahu
Sep 20, 2017·Case Reports in Ophthalmology·Winai Chaidaroon, Sumet Supalaset
Oct 19, 2017·Ocular Immunology and Inflammation·Sumayya AhmadGuillermo Amescua