PMID: 9160031May 1, 1997Paper

Combination intravenous ceftazidime and aminoglycosides in the treatment of pseudomonal scleritis

Ophthalmology
C J HelmB J Mondino

Abstract

Pseudomonal scleritis is a serious and potentially blinding infection that usually is resistant to medical management. Results for three patients with pseudomonal scleritis who were treated with both topical anti-infectives and a combination of intravenous ceftazidime and aminoglycoside are presented in this case series. All three patients had a rapid response to the addition of combination intravenous drug therapy to topical therapy; eradication of the infection and healing of the ocular surface occurred within 8 weeks. Only one patient, in whom cystoid macular edema developed, lost useful vision as a result of the infection. Combination therapy with intravenous ceftazidime and aminoglycoside may be more effective than single-intravenous agents when used in addition to topical antibiotics and may obviate the need for adjunctive surgical procedures, such ascryotherapy, surgical extirpation, or conjunctival recession.

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Citations

Dec 21, 2006·Japanese Journal of Ophthalmology·Wataru SaitoShigeaki Ohno
Aug 14, 2009·American Journal of Ophthalmology·Pooja V BhatC Stephen Foster
Aug 25, 2004·Survey of Ophthalmology·Paris G TranosCarlos E Pavesio
Jan 13, 2000·Cornea·F C HuangS H Tseng
Sep 15, 2005·Cornea·Kamal FahimShahzad I Mian
Dec 7, 2005·Cornea·Jayter Silva PaulaAntonio Augusto Velasco Cruz
Sep 3, 2009·Cornea·Marta Moreno HonradoJosé A Buil
Jun 23, 2011·Cornea·Matthew A CunninghamKirk R Wilhemus
Jan 1, 2010·BMJ Case Reports·Deric De Wit, Douglas Newman
Aug 6, 1999·The British Journal of Ophthalmology·S O SykesE T Cunningham
Feb 16, 2013·Survey of Ophthalmology·Rishi R DoshiEmmett T Cunningham
Jun 22, 2005·Survey of Ophthalmology·Narciss OkhraviSusan Lightman
Sep 20, 2017·Case Reports in Ophthalmology·Winai Chaidaroon, Sumet Supalaset
Oct 19, 2017·Ocular Immunology and Inflammation·Sumayya AhmadGuillermo Amescua

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