Abstract
In general, acute immobilization stress increases plasma corticosterone levels that signal the hypothalamic-pituitary-adrenal axis. Mineralocorticoid receptors and glucocorticoid receptors in the hippocampus perform crucial roles in this feedback mechanism. In the present study, we investigated the effects of chewing under stress on the rat hippocampal mineralocorticoid and glucocorticoid receptors by immunohistochemistry. We separated rats into a control group, a 2-h immobilization stress group (stress only group), and a 2-h immobilization stress group that was allowed to chew on a wooden stick for the latter 1h (stress with chewing group). Mineralocorticoid receptor immunoreactive cells with nucleus staining in the hippocampal CA1 area were scattered in the pyramidal cell layer. The stress only group showed the densest distribution of immunoreactive cells; however, the density of the immunoreactive cells in the stress with chewing group was similar to that of the control group. Changes in immunoreactive cell density were not visible in other areas of the hippocampus, namely, the CA3 area and dentate gyrus. Image analysis indicated that the increase in the mineralocorticoid receptor immunoreactive area within a fixed area in t...Continue Reading
References
Nov 1, 1989·Molecular Endocrinology·J P HermanS J Watson
Feb 1, 1989·Neuron·R M Evans, J L Arriza
Dec 1, 1985·Endocrinology·J M Reul, E R de Kloet
Aug 1, 1986·Endocrine Reviews·R M SapolskyB S McEwen
Oct 1, 1986·Physiology & Behavior·J P Kroon, A L Riley
Jan 1, 1984·Endocrinology·R M SapolskyB S McEwen
Feb 1, 1995·Neuroendocrinology·J P HermanC Prewitt
Mar 1, 1997·Neuroendocrinology·J M ReulF Holsboer
Jun 17, 1998·Endocrine Reviews·E R De KloetM Joëls
Apr 15, 1999·Annual Review of Neuroscience·B S McEwen
Oct 19, 2000·Brain Research. Molecular Brain Research·M E PaskittiJ P Herman
Oct 31, 2002·Journal of Dental Research·M OnozukaS Saito
Jan 18, 2003·Sleep Medicine Reviews·Gaby Bader, Gilles Lavigne
Jan 27, 2004·Journal of Dental Research·N HoriK Tamura
Nov 9, 2004·The Journal of Endocrinology·Alistair I FreemanKaren E Chapman
Jan 29, 2005·Wiener medizinische Wochenschrift·Rudolf Slavicek, Sadao Sato
May 7, 2005·Neuroscience Letters·Kenichi SasaguriSadao Sato
Jun 24, 2005·Journal of Dental Research·N HoriS Sato
Jan 15, 2008·Brain Research·Taeki LeeKeiichi Tsukinoki
Mar 4, 2008·Stress : the International Journal on the Biology of Stress·A StamatakisF Stylianopoulou
Mar 19, 2008·Progress in Neurobiology·Hymie AnismanShawn Hayley
May 6, 2008·Neuroscience Letters·K YamadaT Yamamoto
Jun 7, 2008·Neuroscience·Y OnoM Onozuka
Sep 13, 2008·Acta Histochemica Et Cytochemica·Du ZheShi Yuxiu
Jul 28, 2009·Neuroscience and Biobehavioral Reviews·Melly S OitzlE Ronald de Kloet
Citations
May 20, 2015·Neuroscience Letters·Kentaro YamadaToshiharu Yamamoto
Dec 21, 2013·Neuroscience Letters·Mika OnishiKin-Ya Kubo
Oct 30, 2016·Brain Research·Ayumi SuzukiKin-Ya Kubo
Aug 5, 2017·International Journal of Molecular Sciences·Kagaku AzumaKin-Ya Kubo