Combination of precolumn nitro-reduction and ultraperformance liquid chromatography with fluorescence detection for the sensitive quantification of 1-nitronaphthalene, 2-nitrofluorene, and 1-nitropyrene in meat products

Journal of Agricultural and Food Chemistry
Kailin DengWan Chan

Abstract

Carcinogenic nitropolycyclic aromatic hydrocarbons (nitro-PAHs) are ubiquitous in the ambient environment. They are emitted predominantly from internal combustion engines and by reacting polycyclic aromatic hydrocarbons with nitrogen oxide. The emerging evidence that nitro-PAHs are taken up by plants and bioaccumulatd in the food chain has aroused worldwide concerns for the potential of chronic poisoning through dietary intake. Therefore, analytical methods of high sensitivity are extremely important for assessing the risk of human exposure to nitro-PAHs. This paper describes the development of a simple and robust ultraperformance liquid chromatography coupled fluorescence detector (UPLC-FLD) method for the sensitive determination of nitro-PAHs in meat products. The method entails precolumn reduction of the otherwise nonfluorescent nitro-PAHs to amino-PAHs which strongly fluoresce for their determination by UPLC-FLD analysis. The developed method was validated for extraction efficiency, accuracy, precision, and detection limit and has been successfully applied in quantifying 1-nitronaphthalene (1-NN), 2-nitrofluorene (2-NF), and 1-nitropyrene (1-NP) in fresh and cured meat products. The results showed that the combination of Fe...Continue Reading

References

Jan 1, 1984·Food Additives and Contaminants·M J DennisM E Knowles
Jul 1, 1996·Zeitschrift Für Lebensmittel-Untersuchung Und -Forschung·S Schlemitz, W Pfannhauser
Nov 1, 1996·Food Additives and Contaminants·S Schlemitz, W Pfannhauser
Nov 3, 1998·Archives of Disease in Childhood·S Yalçin, S S Yalçin
May 4, 1999·Mutation Research·I Zwirner-Baier, H G Neumann
Aug 24, 2000·Chemical Research in Toxicology·V Purohit, A K Basu
Dec 2, 2000·Chemosphere·X Jinhui, F S Lee
Jun 9, 2006·Analytical and Bioanalytical Chemistry·Barbara Zielinska, Shar Samy
Jan 12, 2008·Environmental Science & Technology·Manolis Tsapakis, Euripides G Stephanou
Jun 13, 2008·Environmental Science & Technology·Norbert V HeebAndreas Mayer
May 1, 1995·Environmental Science & Technology·J SasakiW P Harger
Mar 15, 2012·Journal of Agricultural and Food Chemistry·Maryuri T Nuñez De GonzálezJimmy T Keeton
Jun 13, 2014·Journal of Agricultural and Food Chemistry·Yinan Wang, Wan Chan

❮ Previous
Next ❯

Citations


❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.