Sep 1, 1975

Combination of R3365 (piritramide) and dehydrobenzperidol in animals. Respiratory effects and analgesia

Annales de l'anesthésiologie française
P CourtoisC Dumas

Abstract

1 -- Respiratory depression has been studied in the no anaesthetized rabbit by analysis of the blood gases after an injection of Piritramide (R 3365) and dehydrobenzperidol. 2 -- The respiratory depression induced by Piritramide alone is less important after an injection of dehydrobenzperidol; the most interessant cases are: -- mixture dehydrobenzperidol 400 mug/kg. Pirittramide 1000 mug/kg; --dehydrobenzperidol (400 mug/kg) injected 15 minutes before Piritramide (1000 mug/kg). 3 -- The addition of Dehydrobenzperidol does not take the analgesic activity of Piritramide decrease by it increases it.

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Mentioned in this Paper

Inapsine
Depression, Chemical
Piperidines
Chinchilla Rabbits
Respiration
Drug Augmentation
Metazoa
Antinociceptive Agents
Isonipecotic Acids
Drug Combinations

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