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Combinations of antifungals to effectively kill drug-resistant Candida auris

bioRxiv

Sep 26, 2019

Siddharth JaggavarapuDavid S Weiss

Abstract

Candida auris is an emerging, highly virulent fungal pathogen that is often resistant to multiple classes of antifungals. To overcome this resistance, we investigated the in vitro efficacy of antifungal combinations, finding that amphotericin B/micafungin resulted in drastically reduced...read more

Mentioned in this Paper

Combination Drug Therapy
Antibiotics, Antifungal
Candida (fungus)
Micafungin
Isolate - Microorganism
Fungi
Virulence Factors
Drug Resistance
Candida auris
6
2
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Combinations of antifungals to effectively kill drug-resistant Candida auris

bioRxiv

Sep 26, 2019

Siddharth JaggavarapuDavid S Weiss

DOI: 10.1101/776096

Abstract

Candida auris is an emerging, highly virulent fungal pathogen that is often resistant to multiple classes of antifungals. To overcome this resistance, we investigated the in vitro efficacy of antifungal combinations, finding that amphotericin B/micafungin resulted in drastically reduced...read more

Mentioned in this Paper

Combination Drug Therapy
Antibiotics, Antifungal
Candida (fungus)
Micafungin
Isolate - Microorganism
Fungi
Virulence Factors
Drug Resistance
Candida auris
6
2

Feeds With Similar Papers

Virulence Factors

Virulence factors are molecules that are produced by organisms including bacteria, viruses, and fungi. They assist the organism in colonization, dissemination, and enhance the ability to survive in harsh environments and evade the host immune system. Discover the latest research on virulence factors here.

BioRxiv Preprints

BioRxiv is the preprint server for biology, operated by Cold Spring Harbor Laboratory. Here are the latest biology preprint articles from bioRxiv.

Related Papers

Journal of Chemotherapy

In vitro activity of amphotericin B against Candida lusitaniae clinical isolates

Journal of ChemotherapyMarch 17, 2010
A PrigitanoA M Tortorano
International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases

Candida auris: An emerging multidrug-resistant pathogen

International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious DiseasesSeptember 11, 2017
David Sears, Brian S Schwartz
Paper Details
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  • Citations
  • finger pointing at paper

    References currently unavailable

    We're still populating references for this paper, please check back later.
  • References
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