Combined angiography and perfusion using radial imaging and arterial spin labeling

Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine
Thomas W Okell

Abstract

To demonstrate the feasibility of a novel noninvasive MRI technique for the comprehensive evaluation of blood flow to the brain: combined angiography and perfusion using radial imaging and arterial spin labeling (CAPRIA). In the CAPRIA pulse sequence, blood labeled with a pseudocontinuous arterial spin labeling pulse train is continuously imaged as it flows through the arterial tree and into the brain tissue using a golden ratio radial readout. From a single raw data set, this flexible imaging approach allows the reconstruction of both high spatial/temporal resolution angiographic images with a high undersampling factor and low spatial/temporal resolution perfusion images with a low undersampling factor. The sparse and high SNR nature of angiographic images ensures that radial undersampling artifacts are relatively benign, even when using a simple regridding image reconstruction. Pulse sequence parameters were optimized through sampling efficiency calculations and the numerical evaluation of modified pseudocontinuous arterial spin labeling signal models. A comparison was made against conventional pseudocontinuous arterial spin labeling angiographic and perfusion acquisitions. 2D CAPRIA data in healthy volunteers demonstrated th...Continue Reading

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Citations

Sep 21, 2019·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·S Sophie SchaumanThomas W Okell
Aug 2, 2020·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Zhensen ChenNiranjan Balu
Nov 26, 2019·Magnetic Resonance in Medical Sciences : MRMS : an Official Journal of Japan Society of Magnetic Resonance in Medicine·Yuriko SuzukiMatthias J P van Osch
May 4, 2021·NMR in Biomedicine·Merlijn C E van der PlasMatthias J P van Osch
May 13, 2021·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Yang LiHanzhang Lu

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