Combined Approach to Treat Medication-Related Osteonecrosis of the Jaws

Journal of Lasers in Medical Sciences
E MerigoCarlo Fornaini

Abstract

Introduction: The proper therapeutic plan for medication-related osteonecrosis of the Jaw (MRONJ) is still lacking long-term data up to today. They were several high-technological appliances proposed for the different intervention steps, in addition to tissue repair promoters. The reason for proposing an integrated technique is justified, beyond better compliance of the patients associated to the pain and inflammation reduction and bleeding control, there is also achieving better hard and soft tissues healing. Methods: Patients diagnosed with bisphosphonates-related osteonecrosis of the jaws (BRONJ) at the Odontostomatology and Maxillo-Facial Surgery Unit of the Hospital of Piacenza undergone surgical intervention. The intervention was performed by using different devices: Piezosurgery for removing the necrotic bone tissue and for obtaining the bone specimen essential for histological analysis; Er:YAG laser (2940 nm) to vaporize necrotic hard tissue until reaching the bleeding bone; platelet-rich plasma (PRP) to stimulate hard and soft tissue healing; and finally diode laser (808 nm) to perform a biostimulation of the surgical site. Results: All treated patients demonstrated a good postoperative comfort even without using paink...Continue Reading

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Citations

Sep 11, 2019·Head & Neck·Elen de Souza TolentinoMariliani C da Silva
Dec 25, 2019·Photobiomodulation, Photomedicine, and Laser Surgery·Katayoun A M KalhoriReza Fekrazad
Dec 9, 2020·Expert Opinion on Drug Safety·Maria V Deligiorgi, Dimitrios T Trafalis
Jul 14, 2020·The Journal of Oral Implantology·Jean-Paul RoccaElisabetta Merigo
May 24, 2021·Brazilian Journal of Otorhinolaryngology·Onur ŞahinOnur Odabaşı

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