Abstract
Eight patients, aged 1 to 8 years, with discrete subaortic stenosis (DSS) and ventricular septal defect (VSD) were studied by 2-dimensional (2-D) and M-mode echocardiography. Initial cardiac catheterization and angiocardiography showed VSD and other associated cardiac lesions, including coarctation of the aorta and patent ductus arteriosus. None had evidence of DSS. Six patients underwent surgical repair of the associated lesions, but none required closure of the VSD. Ultimately, 6 patients had spontaneous closure of VSD, and 2 had a residual small VSD. Subsequent serial echocardiography showed evidence of subaortic membrane, prompting repeat cardiac catheterization, which confirmed moderate to severe peak systolic pressure gradients between the left ventricle and ascending aorta. Surgical resection of the membrane was performed in 5 patients. Thus, in patients with small or spontaneously closed VSDs, DSS may develop. Evaluation of the left ventricular outflow tract area is recommended in patients with small or closed VSD in whom a significant heart murmur or electrocardiographic abnormality remains.
References
Dec 1, 1977·Circulation·N M KatzR R Liberthson
Feb 1, 1979·British Heart Journal·F J Ten CateJ Roelandt
May 1, 1979·The American Journal of Cardiology·T E BerryM H Paul
Mar 1, 1979·Circulation·S K KruegerR L Popp
Mar 1, 1979·Circulation·L W LangeS J Goldberg
Mar 4, 1976·The American Journal of Cardiology·A E WeymanS Chang
Mar 1, 1976·Circulation·C C CaudillW F Weaver
Jul 1, 1973·Circulation·M D FreedA S Nadas
May 1, 1971·Circulation·R L ReisA G Morrow
Jul 1, 1970·The American Journal of Cardiology·R Van PraaghR A Nebesar
Oct 1, 1969·The Journal of Pediatrics·P J Varghese, R D Rowe
Aug 1, 1981·The American Journal of Cardiology·G Ben-ShacherJ E Edwards
Jul 1, 1960·Circulation·R M LAUERJ E EDWARDS
Citations
Sep 1, 1994·British Heart Journal·D KitchinerA Smith
Mar 5, 2013·Pediatric Cardiology·Fahrettin UysalErgun Cil
Jan 31, 2012·Interactive Cardiovascular and Thoracic Surgery·Shinji KanemitsuHideto Shimpo
Aug 1, 1989·International Journal of Cardiology·A CabreraE Pastor
Apr 1, 1992·Journal of the American College of Cardiology·M A FrommeltF M Lupinetti
Jul 1, 1997·Journal of the American College of Cardiology·E G CapeP J del Nido
Jul 1, 1997·Journal of the American College of Cardiology·G SigfússonE G Cape
Aug 31, 2001·Journal of the American College of Cardiology·J M OliverJ M Mesa
Feb 1, 1995·Journal of the American College of Cardiology·N H SilvermanR H Anderson
Sep 1, 1993·The American Journal of Cardiology·M H WuH C Lue
Feb 7, 1995·Echocardiography·D A Danford
Jan 1, 1996·Surgical and Radiologic Anatomy : SRA·N Içten, S Tetik
Jun 1, 1987·Circulation·P ZielinskyR Rodrigues
Aug 1, 1991·British Heart Journal·K Y ChanD G Gibson
Apr 23, 2005·Cardiology in the Young·Robert M FreedomWilliam G Williams
Aug 1, 1985·World Journal of Surgery·C S Weldon
Jul 14, 1988·The New England Journal of Medicine