Combined Dual-Kidney Liver Transplantation in the United States: A Review of United Network for Organ Sharing/Organ Procurement and Transplantation Network Data Between 2002 and 2012

Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society
Grigoriy ShekhtmanSuphamai Bunnapradist

Abstract

In kidney-alone recipients, dual-kidney transplantation using "higher-risk" donor organs has shown outcomes comparable to those of single-kidney transplantation using extended criteria donor (ECD) organs. To investigate the feasibility of a similar approach with combined kidney-liver transplantation, we identified 22 dual-kidney liver transplantations (DKLTs) and 3044 single-kidney liver transplantations (SKLTs) performed in the United States between 2002 and 2012 using United Network for Organ Sharing/Organ Procurement and Transplantation Network registry data. We compared donor/recipient characteristics as well as graft/recipient survival between DKLT recipients and SKLT recipients of "higher-risk" kidneys (ECD and high kidney donor profile index [KDPI; >85%] donors). Despite having overall similar donor and recipient characteristics compared with both "higher-risk" donor groups, recipient survival in the DKLT group at 36 months was markedly inferior at 40.9% (compared with 67.5% for ECD SKLT recipients and 64.5% for high-KDPI SKLT recipients); nondeath-censored graft survival did not differ. Death was the most common cause of graft loss in all groups. Contrary to dual-kidney transplantation data in kidney-alone recipients, D...Continue Reading

References

Mar 17, 2006·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·S FengR M Merion
May 6, 2009·Annals of Internal Medicine·Andrew S LeveyUNKNOWN CKD-EPI (Chronic Kidney Disease Epidemiology Collaboration)
Apr 3, 2012·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Eric F MartinKia Saeian
Jul 25, 2012·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·M K NadimY S Genyk
Jun 13, 2015·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Pratima SharmaJohn C Magee
Nov 26, 2015·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Richard N FormicaDavid Mulligan
Apr 27, 2016·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Marco Di LaudoAntonio Daniele Pinna

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Citations

Sep 27, 2018·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Kara WalterLena Sibulesky
Apr 1, 2018·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Stuart M FlechnerAmy D Waterman
Jul 20, 2019·Transplant International : Official Journal of the European Society for Organ Transplantation·Kevin BuiSanjay Mehrotra
Jun 16, 2019·Journal of Clinical Psychology in Medical Settings·Jessica L HamiltonWinston Dunn
Aug 16, 2018·BMC Medical Ethics·Rachel Grace Son, Susan M Setta
Jul 25, 2019·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Rebecca HaysDianne LaPointe Rudow
Jun 4, 2019·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Barry H TrachtenbergJerry D Estep
Apr 11, 2019·Transplant International : Official Journal of the European Society for Organ Transplantation·Miah T LiSumit Mohan
Oct 3, 2019·NeoReviews·Ai-Ris Y Collier, Rose L Molina
Feb 2, 2018·Circulation·Emelia J BenjaminUNKNOWN American Heart Association Council on Epidemiology and Prevention Statistics Committee and Stroke Statistics Subcommittee
Aug 23, 2019·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Marc PuigvehíBehnam Saberi
Dec 19, 2018·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Steven F SolgaKimberly A Forde
Sep 26, 2019·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Macey L HendersonMatthew Cooper
Nov 21, 2018·Nature Reviews. Nephrology·Stanislas PolMichel Jadoul
May 24, 2019·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Jayme E Locke, Marty T Sellers
Mar 13, 2019·Clinical Journal of the American Society of Nephrology : CJASN·Krista L LentineDorry L Segev
Nov 16, 2019·Transplant International : Official Journal of the European Society for Organ Transplantation·Mario SpaggiariIvo Tzvetanov
Nov 11, 2019·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Jin GeJennifer C Lai
Nov 24, 2019·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Maria IbrahimDarren Stewart
Feb 1, 2019·Circulation·Emelia J BenjaminUNKNOWN American Heart Association Council on Epidemiology and Prevention Statistics Committee and Stroke Statistics Subcommittee
Mar 14, 2018·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Rebecca MillerJoseph D Tobias
Feb 6, 2020·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Jesse SussellBertram L Kasiske
Oct 17, 2019·AJOB Empirical Bioethics·Sarah E Van Pilsum RasmussenJeremy Sugarman
Jan 30, 2020·Circulation·Salim S ViraniUNKNOWN American Heart Association Council on Epidemiology and Prevention Statistics Committee and Stroke Statistics Subcommittee
Sep 11, 2019·JAMA : the Journal of the American Medical Association·L Ebony BoulwareNeil R Powe
Feb 26, 2019·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Lara C Pullen
Oct 5, 2017·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Ryan A DenuNorman Fost
Oct 5, 2019·Tuberculosis and Respiratory Diseases·Kyung Wook JoTae Sun Shim
Jun 26, 2020·MMWR. Recommendations and Reports : Morbidity and Mortality Weekly Report. Recommendations and Reports·Jefferson M JonesSridhar V Basavaraju
Sep 8, 2020·Transplant Infectious Disease : an Official Journal of the Transplantation Society·Nicole M TheodoropoulosMarian G Michaels
Aug 15, 2018·Journal of Medical Ethics·Michael Nair-Collins
Sep 30, 2020·Circulation. Cardiovascular Quality and Outcomes·Supriya ShoreBrahmajee K Nallamothu
Apr 19, 2019·Clinical Journal of the American Society of Nephrology : CJASN·Claire FrancozMitra K Nadim
Sep 25, 2020·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Gabriel R VeceJennifer Wainright
Feb 18, 2021·Current Opinion in Organ Transplantation·Burcin Ekser, William C Goggins

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