Combined EEG/MEG can outperform single modality EEG or MEG source reconstruction in presurgical epilepsy diagnosis

PloS One
Ümit AydinC H Wolters

Abstract

We investigated two important means for improving source reconstruction in presurgical epilepsy diagnosis. The first investigation is about the optimal choice of the number of epileptic spikes in averaging to (1) sufficiently reduce the noise bias for an accurate determination of the center of gravity of the epileptic activity and (2) still get an estimation of the extent of the irritative zone. The second study focuses on the differences in single modality EEG (80-electrodes) or MEG (275-gradiometers) and especially on the benefits of combined EEG/MEG (EMEG) source analysis. Both investigations were validated with simultaneous stereo-EEG (sEEG) (167-contacts) and low-density EEG (ldEEG) (21-electrodes). To account for the different sensitivity profiles of EEG and MEG, we constructed a six-compartment finite element head model with anisotropic white matter conductivity, and calibrated the skull conductivity via somatosensory evoked responses. Our results show that, unlike single modality EEG or MEG, combined EMEG uses the complementary information of both modalities and thereby allows accurate source reconstructions also at early instants in time (epileptic spike onset), i.e., time points with low SNR, which are not yet subject...Continue Reading

References

Jun 1, 1992·IEEE Transactions on Bio-medical Engineering·J C MosherR M Leahy
Feb 1, 1989·IEEE Transactions on Bio-medical Engineering·M S Hämäläinen, J Sarvas
Jan 1, 1987·Physics in Medicine and Biology·D Cohen, B N Cuffin
May 1, 1993·Electroencephalography and Clinical Neurophysiology·J C MosherP S Lewis
Jan 1, 1995·Journal of Physiology, Paris·J M Badier, P Chauvel
Mar 1, 1997·Electroencephalography and Clinical Neurophysiology·B J RothS Sato
Mar 1, 1997·IEEE Transactions on Bio-medical Engineering·S B BaumannF M Meno
Sep 29, 1998·Electroencephalography and Clinical Neurophysiology·M FuchsH Buchner
Nov 6, 1998·Electroencephalography and Clinical Neurophysiology·I MerletF Mauguière
May 7, 1999·IEEE Transactions on Bio-medical Engineering·S BailletJ P Hugonin
Dec 3, 1999·IEEE Transactions on Bio-medical Engineering·G HuiskampA C van Huffelen
Jan 1, 2000·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·A CrouzeixJ Pernier
Nov 10, 2000·Brain Topography·M AkhtariW W Sutherling
Sep 27, 2001·Proceedings of the National Academy of Sciences of the United States of America·D S TuchJ W Belliveau
Mar 1, 2002·Human Brain Mapping·Arthur K LiuJohn W Belliveau
May 11, 2002·Brain Topography·M AkhtariW W Sutherling
Dec 13, 2002·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·Paul BoonJacques De Reuck
Jul 24, 2003·Brain : a Journal of Neurology·H StefanJ Romstöck
Jul 26, 2003·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·Gregory L Barkley, Christoph Baumgartner
Aug 29, 2003·IEEE Transactions on Bio-medical Engineering·S GonçalvesF H Lopes da Silva
Oct 31, 2003·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·T E J BehrensS M Smith
Jan 1, 2004·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·Göran LantzChristoph M Michel
May 12, 2004·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Manfred FuchsJörn Kastner
Sep 24, 2004·Brain Topography·Ceon RamonA Ishimaru
Oct 29, 2004·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·Martine GavaretPatrick Chauvel
Nov 26, 2004·Brain : a Journal of Neurology·Michael J M FischerHermann Stefan
Jan 18, 2005·NeuroImage·Ekaterina PataraiaChristoph Baumgartner
Feb 26, 2005·Epilepsia·Katsuhiro KobayashiJean Gotman
Aug 12, 2005·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·Andrew C PapanicolaouPanagiotis G Simos
Jun 27, 2006·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Kamran Ali SalayevKazuie Iinuma
Oct 13, 2006·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Dominik ZumstegRichard A Wennberg
Dec 5, 2006·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·Thomas BastMichael Scherg
Apr 7, 2007·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·Manfred FuchsJoern Kastner
May 10, 2007·Expert Review of Medical Devices·Stefan Rampp, Hermann Stefan
Jul 31, 2007·NeuroImage·Ming-Xiong HuangEric Halgren
Aug 19, 2007·IEEE Transactions on Bio-medical Engineering·Carsten H WoltersUlrich Hartmann

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Citations

Mar 5, 2016·Brain Topography·Victoria Montes-RestrepoPieter van Mierlo
Mar 2, 2016·Lancet Neurology·John S DuncanSebastien Ourselin
Apr 22, 2016·Expert Review of Neurotherapeutics·Raheel Ahmed, James T Rutka
Jun 1, 2017·Brain Sciences·Aina Puce, Matti S Hämäläinen
Mar 28, 2018·Biomedical Engineering Online·Johannes VorwerkCarsten H Wolters
Nov 16, 2016·Physics in Medicine and Biology·S PursiainenC H Wolters
Sep 21, 2018·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·John S Ebersole, Michael Wagner
Aug 19, 2017·Biomedizinische Technik. Biomedical Engineering·Alexander HunoldJens Haueisen
Jun 3, 2016·Epilepsia·Midori NakajimaHiroshi Otsubo
Feb 7, 2020·Clinical and Experimental Pediatrics·Yun Jeong Lee
Apr 22, 2017·Frontiers in Neuroscience·Juan D Martinez-VargasGerman Castellanos-Dominguez
Feb 20, 2018·Frontiers in Neuroscience·Maria Carla PiastraCarsten H Wolters
Feb 23, 2019·Frontiers in Human Neuroscience·Fernando MaestúPaul E Schulz
Jun 30, 2019·Frontiers in Neurology·Rudolf KreidenhuberStefan Rampp
Nov 10, 2020·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·Anto I BagićRichard C Burgess
May 25, 2021·Journal of Neuroscience Methods·Yao MiaoAndrzej Cichocki
Jul 24, 2021·Biomedical Physics & Engineering Express·Grégoire DemoulinMartine Gavaret

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Software Mentioned

EMEG
Freesurfer
DTIFIT
FAIR
BESA
FSL
Matlab
FAST
Curry
SimBio

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