Combined effect of socioeconomic status, viral hepatitis, and lifestyles on hepatocelluar carcinoma risk in Korea.

British Journal of Cancer
E H YunE-C Park

Abstract

The independent and combined effects of socioeconomic status (SES), viral hepatitis, and other lifestyle factors on hepatocellular carcinoma (HCC) risk have not been investigated among Koreans. From the National Cancer Center Hospital, 207 HCC cases and 828 age- and gender-matched controls aged 30 years or older were recruited. Socio-demographic and behavioural risk factors were ascertained through personal interview, and infection with hepatitis B and C viruses was determined by their serologic markers. Multivariate logistic regression and synergy index methods were applied for statistical analysis. HB surface antigen (HbsAg) and anti-HCV-positive rates were 149.3 and 185.1 times higher in cases than controls, respectively. Lifetime alcohol consumption (odds ratio: 2.96, 95% CI: 1.29-6.79), cigarette smoking (OR: 3.53, 95% CI: 1.31-9.52), and family income (OR: 17.07, 95% CI: 4.27-68.25) were independently associated with the risk of HCC in subjects with or without viral hepatitis. Synergistic interaction on HCC risk was observed between low income and HBsAg positivity (SI: 3.12, 95% CI: 1.51-6.47) and between low income and heavy alcohol intake (SI: 2.93, 95% CI: 1.24-6.89). The inverse association with SES suggests SES as an...Continue Reading

References

May 1, 1976·American Journal of Epidemiology·K J Rothman
Mar 1, 1980·Social Science & Medicine·M R GreenbergR Anderson
Feb 10, 1998·International Journal of Cancer. Journal International Du Cancer·F DonatoM Puoti
Feb 24, 2001·Canadian Journal of Gastroenterology = Journal Canadien De Gastroenterologie·M C YuR K Ross
Jul 4, 2002·Annals of the New York Academy of Sciences·Giuseppe MontaltoLuigi A M Castagnetta
Jan 31, 2004·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Gregory D KirkRuggero Montesano
Feb 20, 2004·Public Health Nutrition·Timothy J KeyRuth C Travis
Apr 7, 2004·Preventive Medicine·Giovanni CorraoCarlo La Vecchia
Jun 18, 2004·Alcoholism, Clinical and Experimental Research·Lorraine GunzerathKenneth Warren
Oct 28, 2004·Gastroenterology·Timothy R MorganM Mazen Jamal
Dec 17, 2004·Journal of the National Cancer Institute·Sun Ha JeeJonathan M Samet
Jan 25, 2005·Journal of Hepatology·Jorge A MarreroAnna S Lok
Jul 8, 2005·International Archives of Occupational and Environmental Health·Jianguang Ji, Kari Hemminki
Sep 17, 2005·Intervirology·Hai-Rim Shin
Feb 4, 2006·The Lancet Oncology·Paolo Boffetta, Mia Hashibe
Nov 1, 2006·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Sang Min ParkYoung Ho Yun
Apr 7, 2007·International Journal of Cancer. Journal International Du Cancer·Gwenn MenvielleJohan P Mackenbach
Aug 19, 2007·British Journal of Cancer·S C Larsson, A Wolk
Dec 13, 2007·Journal of the National Cancer Institute·Rune KvåleFreddie Bray
Apr 5, 2008·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Takamasa OhkiMasao Omata
Jul 10, 2008·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Yun-Mi SongMina Ha
Jul 31, 2008·World Journal of Gastroenterology : WJG·Asmaa-Ibrahim GomaaSimon-D Taylor-Robinson
Oct 24, 2008·Japanese Journal of Clinical Oncology·Keitaro TanakaUNKNOWN Research Group for the Development and Evaluation of Cancer Prevention Strategies in Japan
Feb 5, 2009·European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP)·Teresa SpadeaGiuseppe Costa
Dec 1, 2007·Cancer Research and Treatment : Official Journal of Korean Cancer Association·Hai-Rim ShinKeun-Young Yoo

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Citations

Aug 15, 2014·Epidemiology and Health·Jeongseon Kim
Jun 13, 2012·World Journal of Gastroenterology : WJG·Chung-Hwa ParkSeung Kew Yoon
May 10, 2011·Journal of Korean Academy of Nursing·Myungsun YiHyang Sook So
Apr 27, 2018·Cancer Causes & Control : CCC·Trang VoPhamJaime E Hart
Jun 7, 2014·Journal of Evaluation in Clinical Practice·Julie KonfortionRuth H Jack
Jul 3, 2015·Cancer Causes & Control : CCC·Shu-Chun ChuangMia Hashibe
Jan 29, 2020·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Yuanjie PangZhengming Chen
Sep 2, 2021·International Journal for Equity in Health·Dong Jun KimSun Jung Kim

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Methods Mentioned

BETA
enzyme-linked immunosorbent assays

Software Mentioned

SAS

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