Combined effect of strontium and pyrophosphate on the properties of brushite cements

Acta Biomaterialia
M Hamdan AlkhraisatEnrique Lopez Cabarcos

Abstract

In this study we report the synthesis of strontium-containing brushite cement with good cohesion and a diametral tensile strength (DTS) of 5 MPa. The cement powder, composed of beta-tricalcium phosphate (beta-TCP) and monocalcium phosphate, was adjusted by different concentrations of strontium and pyrophosphate ions. The cement liquid phase was 2M phosphoric acid solution. The cement cohesion and mechanical properties were measured after being aged in water for 24h at 37 degrees C. It was found that at low concentration both strontium and pyrophosphate ions inhibit the cement setting reaction. However, the final setting time was significantly reduced when SrCl2 increased from 5 to 10 wt.% at pyrophosphate concentrations equal to or higher than 2.16 wt.%. The incorporation of strontium ions did not increase the DTS of brushite cements significantly. In contrast, the addition of pyrophosphate ions did increase the DTS of brushite cements significantly. When both ions were added simultaneously, the brushite cement with a Sr2+ content of 5 wt.% had the highest DTS value. Nevertheless, the DTS values of Sr-containing cements were significantly reduced if the pyrophosphate concentration was higher than 2.16 wt.%. The Sr2+ ions had a ...Continue Reading

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Citations

Oct 24, 2009·Journal of Materials Science. Materials in Medicine·S PinaJ M F Ferreira
Mar 24, 2010·Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences·Jennifer L GiocondiChristine A Orme
Feb 4, 2016·Materials Science & Engineering. C, Materials for Biological Applications·Jatsue Cabrejos-AzamaEnrique López-Cabarcos
Aug 23, 2011·Acta Biomaterialia·Faleh TamimiJake Barralet
Feb 11, 2010·Acta Biomaterialia·Guilhem RomieuPhilippe Boudeville
Dec 31, 2009·Acta Biomaterialia·E BoaniniA Bigi
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Apr 6, 2021·Frontiers in Bioengineering and Biotechnology·Lijuan SunDagang Guo

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