PMID: 8988923Jan 1, 1997Paper

Combined effects of lipid peroxidation and antioxidant status on carotid atherosclerosis in a population aged 59-71 y: The EVA Study. Etude sur le Vieillisement Artériel

The American Journal of Clinical Nutrition
C Bonithon-KoppP Ducimetière

Abstract

There are few epidemiologic studies of the effects of lipid peroxidation and antioxidant status on atherosclerosis. The relation of lipid peroxidation evaluated by thiobarbituric acid-reactive substances (TBARS) and biological markers of antioxidant status to ultrasonographically assessed carotid atherosclerosis was examined from baseline data of a longitudinal study on cognitive and vascular aging (Etude sur le Vieillisement Artériel, the EVA Study). The study sample was composed of 1187 mean and women aged 59-71 y without any history of coronary artery disease or stroke. Ultrasound examination included measurements of intima-media thickness (IMT) on the common carotid arteries (CCAs) and at the site of plaques. After adjustment for conventional cardiovascular risk factors, erythrocyte vitamin E was significantly and negatively associated with CCA-IMT in both men and women whereas plasma selenium and carotenoids were not. No association was found between TBARS and CCA-IMT in either sex. However, TBARS were significantly higher in men with carotid plaques than in those without. This association was strengthened in men with concentrations of erythrocyte vitamin E, plasma selenium, and carotenoids below the lowest quartile. Our f...Continue Reading

Citations

Dec 21, 2000·Current Atherosclerosis Reports·S Devaraj, I Jialal
Sep 25, 2010·Arteriosclerosis, Thrombosis, and Vascular Biology·Catherine DesrumauxLaurent Lagrost
Dec 16, 2000·Arteriosclerosis, Thrombosis, and Vascular Biology·T RissanenJ T Salonen
Nov 9, 2002·Experimental Biology and Medicine·Tiina RissanenJukka T Salonen
Nov 2, 2001·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·R RicciarelliA Azzi
Jan 26, 2006·Basic & Clinical Pharmacology & Toxicology·Louise A LexisJeff S Coombes
Dec 13, 2005·The Tohoku Journal of Experimental Medicine·Levent Sinan BirMehmet Köseoğlu
Apr 11, 2006·Preventive Cardiology·Christos HatzigeorgiouPatrick G O'Malley
Apr 8, 2010·Critical Reviews in Food Science and Nutrition·Zorabel CorderoHeiner Boeing
Oct 19, 2000·Journal of the American Geriatrics Society·C BerrA Alpérovitch
Aug 29, 2002·The American Journal of Clinical Nutrition·Arcangelo IannuzziPaolo Rubba
Dec 15, 2000·European Journal of Clinical Investigation·F W van den BerkmortelA F Stalenhoef
May 30, 2002·Biological Chemistry·Roberta RicciarelliAngelo Azzi
Jun 27, 2009·Nutrition Research Reviews·Concepción Sánchez-MorenoAntonio Martín
Jun 15, 2001·Journal of the American Geriatrics Society·A CherubiniUNKNOWN VASA Study Group
Oct 24, 1998·Acta Neurologica Scandinavica·N Delanty, M A Dichter
Sep 1, 2005·Basic & Clinical Pharmacology & Toxicology·Louise A LexisJeff S Coombes
Jan 26, 2006·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·L A LexisJ S Coombes
Aug 28, 2001·The American Journal of Clinical Nutrition·C R GaleC N Martyn
Dec 25, 2002·The American Journal of Clinical Nutrition·Tiina H RissanenJukka T Salonen
Feb 13, 2001·The Journal of Nutrition·M Meydani
Mar 14, 2002·Biochemical and Biophysical Research Communications·Ananth Sekher PannalaCatherine A Rice-Evans
Feb 19, 2002·Atherosclerosis·Kyoko NishiShinji Nagahiro
Mar 2, 2002·Journal of Diabetes and Its Complications·Kerin O'Dea, Kevin G Rowley
Dec 12, 2001·Journal of the American College of Cardiology·B M McQuillanP L Thompson
Aug 11, 2000·Chemico-biological Interactions·C S LiuH W Chen
Feb 3, 2000·Free Radical Biology & Medicine·W A Pryor
Nov 30, 2005·Atherosclerosis·A C KalioraH Schmidt
Sep 11, 2007·Molecular Aspects of Medicine·Adelina Munteanu, Jean-Marc Zingg
Aug 25, 2009·Clinica Chimica Acta; International Journal of Clinical Chemistry·Aikaterini T VasilakiDonald C McMillan

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