PMID: 14678133Dec 18, 2003Paper

Combined efficacy of atrial septal lead placement and atrial pacing algorithms for prevention of paroxysmal atrial tachyarrhythmia

Journal of Cardiovascular Electrophysiology
Luigi PadelettiWorldwide ASPECT Investigators

Abstract

The combined role of atrial septal lead location and atrial pacing algorithms in the prevention of atrial tachyarrhythmias (AT/AF), including both atrial fibrillation and flutter, is unknown. We tested the hypothesis that atrial prevention pacing algorithms could decrease AT/AF frequency in patients with atrial septal leads, bradycardia, and paroxysmal AT/AF. A total of 298 patients (age 70 +/- 10 years; 61% male) from 35 centers were implanted with a DDDRP pacing system including three AT/AF prevention pacing algorithms. Lead site was randomized at implant to right atrial septal or nonseptal. Patients were randomized 1 month postimplant to AT/AF prevention ON or OFF for 3 months and then crossed over for 3 months. Patients logged symptomatic AT/AF episodes via a manual activator. Prevention efficacy was evaluated based on intention-to-treat in 277 patients (138 septal) with complete follow-up. No changes in device-recorded AT/AF frequency or burden were observed with algorithms OFF versus ON or between patients randomized to septal versus nonseptal lead location. Analysis of other secondary outcomes revealed that AT/AF prevention pacing resulted in decreased atrial premature contractions in both the septal (1.9 [0.2-8.7] vs 3....Continue Reading

Associated Clinical Trials

References

May 1, 1983·Pacing and Clinical Electrophysiology : PACE·P CoumelJ F Leclercq
Nov 1, 1994·Pacing and Clinical Electrophysiology : PACE·F D MurgatroydP Ritter
Dec 11, 1997·Pacing and Clinical Electrophysiology : PACE·W H SpencerW A Zoghbi
Feb 10, 1998·Pacing and Clinical Electrophysiology : PACE·S ChevalierJ W Leitch
Jun 7, 2000·Journal of the American College of Cardiology·R BeckerW Schoels
Nov 4, 2000·Journal of Cardiovascular Electrophysiology·G R D'AllonnesJ C Daubert
Jan 11, 2000·Stroke; a Journal of Cerebral Circulation·G EngströmL Janzon
Jan 5, 2001·Pacing and Clinical Electrophysiology : PACE·M KindermannG Fröhlig
Sep 8, 2001·The American Journal of Cardiology·C P LauUNKNOWN New Indication for Preventive Pacing in Atrial Fibrillation (NIPP-AF) Investigators
Nov 9, 2001·Journal of Cardiovascular Electrophysiology·C W IsraelUNKNOWN AT500 Verification Study Investigators
Jun 14, 2002·The New England Journal of Medicine·Gervasio A LamasUNKNOWN Mode Selection Trial in Sinus-Node Dysfunction
Oct 2, 2002·Journal of the American College of Cardiology·Sanjeev SaksenaUNKNOWN DAPPAF Investigators

❮ Previous
Next ❯

Citations

Mar 5, 2005·Zeitschrift für Kardiologie·A YangT Lewalter
Jan 18, 2006·Zeitschrift für Kardiologie·G Fröhlig
Apr 13, 2005·Herzschrittmachertherapie & Elektrophysiologie·D Böcker, R Gradaus
Feb 28, 2009·Herzschrittmachertherapie & Elektrophysiologie·C W Israel
Jul 10, 2010·Annals of Biomedical Engineering·Laurent UldryLukas Kappenberger
May 3, 2007·Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing·John Silberbauer, Neil Sulke
Jul 3, 2007·Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing·Andreas SchuchertMichael Gold
Jan 19, 2010·Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing·Rick A VeaseyA Neil Sulke
Jul 19, 2011·Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing·Rangadham NagarakantiLuigi Padeletti
Sep 6, 2005·Current Treatment Options in Cardiovascular Medicine·Gregory K Bruce, Paul A Friedman
Jan 13, 2012·The New England Journal of Medicine·Jeff S HealeyUNKNOWN ASSERT Investigators
Nov 15, 2008·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Helmut PürerfellnerRoger Kessels
May 23, 2009·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Anne M GillisGeorge D Wyse
Aug 4, 2009·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Emmanuel N SimantirakisPanos E Vardas
Jun 12, 2010·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Gerardo NigroRaffaele Calabrò
Mar 26, 2011·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Carsten W Israel
Mar 23, 2012·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Yan HuoPyotr G Platonov
Nov 1, 2012·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Laurent UldryLukas Kappenberger
Mar 26, 2011·Circulation Journal : Official Journal of the Japanese Circulation Society·Ritsuko KohnoYutaka Otsuji
Feb 3, 2011·World Journal of Cardiology·Eraldo OcchettaPaolo Marino
Oct 30, 2008·Netherlands Heart Journal : Monthly Journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation·W G de Voogt, N M van Hemel
Jul 31, 2008·Netherlands Heart Journal : Monthly Journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation·W G de Voogt, N M van Hemel
Jul 31, 2008·Netherlands Heart Journal : Monthly Journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation·I C van Gelder, A C P Wiesfeld
Oct 31, 2015·Pacing and Clinical Electrophysiology : PACE·Simon KochhäuserAtul Verma
Jun 16, 2012·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Stefan H HohnloserUNKNOWN ASSERT Investigators
Apr 17, 2012·The American Journal of Cardiology·A John CammLuigi Padeletti
Jun 6, 2009·Journal of Electrocardiology·Polychronis Dilaveris, Christodoulos Stefanadis
May 26, 2009·American Heart Journal·UNKNOWN RATE Steering Committee, UNKNOWN RATE Investigators
Sep 1, 2009·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Stefano BianchiPaolo Azzolini
Mar 3, 2009·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Anne M Gillis
Mar 3, 2009·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Michael R GoldUNKNOWN SAFARI Investigators
Dec 30, 2008·Cardiology Clinics·Gautham Kalahasty, Kenneth Ellenbogen
Mar 6, 2007·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Kenneth A Ellenbogen
Jul 24, 2004·Pacing and Clinical Electrophysiology : PACE·Helmut PurerfellnerDouglas A Hettrick
Apr 9, 2005·Journal of Cardiovascular Electrophysiology·Mattias DuytschaeverRene Tavernier
Aug 18, 2005·Pacing and Clinical Electrophysiology : PACE·Willem de VoogtJohn Helland
Aug 18, 2005·Pacing and Clinical Electrophysiology : PACE·Azamuddin Khaja, Greg Flaker
Mar 24, 2005·The American Journal of Geriatric Cardiology·Rik Willems, Hein Heidbüchel
May 23, 2009·Journal of Cardiovascular Electrophysiology·Chu-Pak LauUNKNOWN SAFE Study Steering Committee for SAFE Study Group
Jun 11, 2004·Pacing and Clinical Electrophysiology : PACE·Luigi PadelettiNicola Musilli
Jun 11, 2004·Pacing and Clinical Electrophysiology : PACE·Michael D Gammage, Anna-Marie Marsh
Dec 16, 2006·Pacing and Clinical Electrophysiology : PACE·Renato P RicciMassimo Santini
Feb 24, 2006·Pacing and Clinical Electrophysiology : PACE·Thorsten LewalterBerndt Lüderitz

❮ Previous
Next ❯

Related Concepts

Related Feeds

Atrial Filbrillation

Atrial fibrillation refers to the abnormal heart rhythm characterized by rapid and irregular beating of the atria. Here is the latest research.

Arrhythmia

Arrhythmias are abnormalities in heart rhythms, which can be either too fast or too slow. They can result from abnormalities of the initiation of an impulse or impulse conduction or a combination of both. Here is the latest research on arrhythmias.

Ataxia telangiectasia (MDS)

Ataxia telangiectasia is a rare neurodegenerative diseases caused by defects in the ATM gene, which is involved in DNA damage recognition and repair pathways. Here is the latest research on this autosomal recessive disease.

Bradyarrhythmias

Bradyarrhythmias are slow heart rates. Symptoms may include syncope, dizziness, fatigure, shortness of breath, and chest pains. Find the latest research on bradyarrhythmias here.

Atrial Fibrillation

Atrial fibrillation is a common arrhythmia that is associated with substantial morbidity and mortality, particularly due to stroke and thromboembolism. Here is the latest research.

Related Papers

Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology
Jean-Jacques BlancPIPAF Investigators
© 2021 Meta ULC. All rights reserved