PMID: 20623471Jul 14, 2010Paper

Combined Ex-PRESS LR-50/IOL implantation in modified deep sclerectomy plus phacoemulsification for glaucoma associated with cataract

European Journal of Ophthalmology
Fanny GindrozCorinne C Schnyder

Abstract

This is a prospective study reporting on modified deep sclerectomy (DS) using the Ex-PRESS LR-50 in combined cataract and glaucoma surgery. Twenty-four eyes of 24 patients with medically uncontrolled glaucoma underwent modified DS. After phacoemulsification and intraocular lens implantation, the Ex-PRESS LR-50 was inserted into the anterior chamber under a scleral flap. A partial posterior DS was performed to provide an intrascleral bleb. The complete success rate was intraocular pressure (IOP) without medication =18 mmHg; the qualified success rate was IOP =18 mmHg with or without medication. Postoperative bleb management (subconjunctival mitomycin C injections ± needling) was performed in case of postoperative hypertension or bleb fibrosis. Follow-up was 40.1±10.8 (mean ± SD) months. Preoperatively, IOP was 18.1±5.3 mmHg, best-corrected visual acuity (BCVA) was 0.6±0.3, and number of medications was 2.3±1.1. The IOP decreased by 25.4% at 24 months and by 27.0% at 48 months. At 24 months, 19 patients (86.3%) achieved a BCVA of 0.5 or better, and at 48 months the mean BCVA was 0.7±0.3. At the last visit, the mean number of medications was 0.6±0.8 (p<0.05). The complete and qualified success rates were 45.6% and 85.2%. Mitomycin...Continue Reading

References

Apr 21, 1999·The British Journal of Ophthalmology·M E KarlenA Mermoud
Mar 10, 2000·International Ophthalmology Clinics·S Bylsma
Nov 16, 2001·Journal of Cataract and Refractive Surgery·T ShaarawyA Mermoud
Jun 5, 2003·Journal of Glaucoma·Abraham NyskaYoram Epstein
Nov 12, 2003·The British Journal of Ophthalmology·T DelariveA Mermoud
Dec 25, 2003·The British Journal of Ophthalmology·T ShaarawyA Mermoud
Jun 5, 2004·Journal of Cataract and Refractive Surgery·Tarek ShaarawyAndré Mermoud
Mar 3, 2005·Journal of Glaucoma·Elie Dahan, Trevor R Carmichael
Jul 26, 2005·American Journal of Ophthalmology·Michael W StewartBrian L Schwam
Aug 10, 2005·American Journal of Ophthalmology·Richard M StewartRamesh S Ayyala
Sep 15, 2005·Archives of Ophthalmology·Sunir J GargDavid Fischer
Feb 21, 2006·The British Journal of Ophthalmology·H A Quigley, A T Broman
Jan 17, 2007·Journal of Glaucoma·Peter J G MarisPeter A Netland
Oct 30, 2007·Journal of Cataract and Refractive Surgery·Delphine RivierAndré Mermoud
Dec 19, 2008·Journal of Glaucoma·Alexandre BissigSylvain Roy

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Citations

Dec 18, 2013·European Journal of Ophthalmology·Gábor Holló, Farzaneh Naghizadeh
Apr 26, 2015·Survey of Ophthalmology·Tarek ShaarawyRobert Fechtner
Jun 5, 2021·Saudi Journal of Ophthalmology : Official Journal of the Saudi Ophthalmological Society·Mohammad A AlSemariEssam A Osman

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