Combined pharmacotherapy and psychological treatment for depression: a systematic review

Archives of General Psychiatry
Sandro PampallonaCarmine Munizza

Abstract

Adherence to antidepressant medication use is a problem in clinical practice. Some authors have posited that combined psychological treatment facilitates adherence to pharmacotherapy. To study the relationship between adherence to use of and efficacy of antidepressant drugs plus psychological treatment vs drug treatment alone in depressive disorders. MEDLINE, Current Contents, PsychInfo, Cochrane Library, and reference lists were searched, from January 1980 to November 2002. Randomized clinical trials comparing antidepressant treatment alone with antidepressant treatment in combination with a psychological intervention in depressive disorders were considered. The decision to include studies in the meta-analysis was performed by 2 reviewers. Three independent reviewers extracted the data, using a precoded form. Methodological quality of the studies was evaluated in terms of allocation concealment and independence of evaluators. Sixteen trials met the inclusion criteria, with 932 patients randomized to pharmacotherapy alone and 910 to combined treatment. Overall, patients receiving combined treatment improved significantly compared with those receiving drug treatment alone (odds ratio [OR], 1.86; 95% confidence interval [CI], 1.3...Continue Reading

Citations

Apr 1, 2014·Journal of Affective Disorders·Kateri McRaeJames J Gross
Jan 11, 2014·Annual Review of Psychology·W Edward Craighead, Boadie W Dunlop
Feb 8, 2014·European Psychiatry : the Journal of the Association of European Psychiatrists·S MayerC Schüle
Jun 8, 2014·Social Psychiatry and Psychiatric Epidemiology·Margot J Schofield, Asaduzzaman Khan
Nov 3, 2009·The Clinical Neuropsychologist·Thomas W McAllister
Apr 2, 2010·The British Journal of Psychiatry : the Journal of Mental Science·S A H GerhardsS M A A Evers
Dec 2, 2010·The British Journal of Psychiatry : the Journal of Mental Science·Bernadka DubickaIan M Goodyer
Jul 12, 2008·Journal of General Internal Medicine·Michael LindenChristiane Rentzsch
Jan 16, 2008·Annals of Family Medicine·James E AikensMichael S Klinkman
May 20, 2008·BMC Psychiatry·Pim CuijpersGerhard Andersson
Dec 3, 2010·Psychiatric Services : a Journal of the American Psychiatric Association·Susan L EttnerMichael K Ong
Aug 13, 2011·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Michael BrowningCatherine J Harmer
Jun 23, 2010·Current Psychiatry Reports·Dan J Stein, Jonathan C Ipser
May 26, 2012·Current Psychiatry Reports·Cássio M C BottinoSalma R I Ribeiz
Jan 11, 2011·The Journal of the American Academy of Psychoanalysis and Dynamic Psychiatry·Richard C Friedman
Sep 26, 2008·Psychotherapy Research : Journal of the Society for Psychotherapy Research·Pim CuijpersNiels Smits
Apr 8, 2009·Journal of Neural Transmission·Joseph P HustonBianca Topic
Mar 16, 2013·Der Nervenarzt·I GroßimlinghausJ Zielasek
Oct 28, 2005·The New England Journal of Medicine·J John Mann
Sep 26, 2012·Psychodynamic Psychiatry·Larry S Sandberg, Fredric N Busch
Sep 4, 2009·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·S M Baskin, Todd A Smitherman
May 6, 2011·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Steven M Baskin, Todd A Smitherman
Jun 6, 2006·The Journal of Behavioral Health Services & Research·Francisca Azocar, Robert B Branstrom
Jan 3, 2015·International Review of Psychiatry·Jane Walker, Michael Sharpe
Aug 3, 2010·Postgraduate Medicine·Robert H Howland
Nov 30, 2011·International Journal of Psychiatry in Clinical Practice·Michael Linden, Anja Westram
Oct 31, 2014·Journal of Mental Health·Rasika JayasekaraKate Deuter
Dec 26, 2006·Expert Review of Neurotherapeutics·Hanne Vibe Hansen, Lars Vedel Kessing
Jul 11, 2009·Expert Review of Neurotherapeutics·Maurizio PompiliDavid Lester
Nov 5, 2015·Drug Development and Industrial Pharmacy·Simay YıldızNurşen Ünlü

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.