Combined training improves walking mobility in persons with significant disability from multiple sclerosis: a pilot study

Journal of Neurologic Physical Therapy : JNPT
R W MotlJacob J Sosnoff

Abstract

The disabling consequences of multiple sclerosis (MS) emphasize the significance of developing physiologically relevant strategies for rehabilitation of function. This pilot study examined changes in walking function associated with combined exercise training consisting of aerobic, resistance, and balance activities in persons with MS who had recent onset of gait impairment. Thirteen participants with significant disability due to MS (Expanded Disability Status Scale range = 4.0-6.0) completed the Multiple Sclerosis Walking Scale-12, 2 trials of the Timed 25-Foot Walk, the Timed Up & Go, and functional ambulation profile score derived from 4 walking trials on an instrumented walkway (GaitRite) before and after an 8-week training period. The training program was designed by a physical therapist and was performed 3 days per week under the supervision of an exercise specialist. In week 1, the session was 15 minutes in duration (ie, 5 minutes of each mode of exercise), session durations were increased by approximately 5 minutes per week up to a maximum of 60 minutes in week 8 (ie, 20 minutes of each mode of exercise). There were significant improvements in Multiple Sclerosis Walking Scale-12 scores (Mpre = 56.0, Mpost = 46.7, P = 0...Continue Reading

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Nov 5, 2011·Journal of Neurologic Physical Therapy : JNPT·Alon KalronZeevi Dvir

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Citations

Jul 18, 2015·International Journal of Molecular Sciences·Arno KerlingAnja Windhagen
Oct 26, 2013·Multiple Sclerosis : Clinical and Laboratory Research·S BrikenC Heesen
Jul 25, 2012·Nature Reviews. Neurology·Robert W Motl, Lara A Pilutti
Mar 23, 2013·Physical Therapy·Parminder K Padgett, Susan L Kasser
Mar 15, 2015·American Journal of Physical Medicine & Rehabilitation·Inez WensBert O Eijnde
Mar 19, 2016·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·I WensB O Eijnde
Aug 29, 2020·Journal of Foot and Ankle Research·Minna StoltHelena Leino-Kilpi
Aug 8, 2015·Journal of Neurologic Physical Therapy : JNPT·Brenda L DaviesMax J Kurz
Jan 1, 2017·Physiotherapy Canada. Physiothérapie Canada·Shahid Escudero-UribeGuillermo Izquierdo-Ayuso

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