Combined transcranial magnetic stimulation in the treatment of chronic tinnitus

Annals of Clinical and Translational Neurology
Martin FormánekPavel Komínek

Abstract

Repetitive transcranial magnetic stimulation (rTMS) is currently being tested for suppressing the symptoms of subjective chronic primary tinnitus, although its effect is controversial. The aim of this randomized double-blinded controlled trial was to determine the effect of rTMS with unique settings for tinnitus treatment. Fifty-three adult patients suffering from chronic subjective unilateral or bilateral nonpulsatile primary tinnitus for at least 6 months were randomly assigned to rTMS (group 1, n = 20), sham stimulation (group 2, n = 12), or medicament therapy only (group 3, n = 21). The dorsolateral prefrontal cortex (frequency 25 Hz, 300 pulses, and 80% resting motor threshold [RMT]) on the left side and primary auditory cortex (1 Hz, 1000 pulses, 110% RMT) were stimulated on both sides in patients in group 1 for 5 consecutive days. The Tinnitus Reaction Questionnaire (TRQ), Tinnitus Handicap Questionnaire (THQ), Tinnitus Handicap Inventory (THI), Beck Depression Inventory (BDI), pure-tone audiometry with Fowler scoring of hearing loss, and tinnitus analysis were used to evaluate tinnitus in all patients. Data were recorded the day the patient was included in the study and at 1- and 6-month follow-up. The study groups were...Continue Reading

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Citations

Aug 23, 2019·Scientific Reports·Stefan SchoisswohlMartin Schecklmann
Jul 21, 2020·Neural Plasticity·Kunkun WangShan Sun
Dec 5, 2020·Brain Stimulation·Mathilde Lefebvre-DemersShirley Fecteau
Jan 7, 2020·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Jean-Pascal LefaucheurUlf Ziemann
Mar 18, 2021·The Journal of International Medical Research·Lu YinJuntao Yan
Jun 29, 2021·Frontiers in Aging Neuroscience·Jorge Piano SimoesEleni Genitsaridi

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