Abstract
Repetitive transcranial magnetic stimulation (rTMS) is currently being tested for suppressing the symptoms of subjective chronic primary tinnitus, although its effect is controversial. The aim of this randomized double-blinded controlled trial was to determine the effect of rTMS with unique settings for tinnitus treatment. Fifty-three adult patients suffering from chronic subjective unilateral or bilateral nonpulsatile primary tinnitus for at least 6 months were randomly assigned to rTMS (group 1, n = 20), sham stimulation (group 2, n = 12), or medicament therapy only (group 3, n = 21). The dorsolateral prefrontal cortex (frequency 25 Hz, 300 pulses, and 80% resting motor threshold [RMT]) on the left side and primary auditory cortex (1 Hz, 1000 pulses, 110% RMT) were stimulated on both sides in patients in group 1 for 5 consecutive days. The Tinnitus Reaction Questionnaire (TRQ), Tinnitus Handicap Questionnaire (THQ), Tinnitus Handicap Inventory (THI), Beck Depression Inventory (BDI), pure-tone audiometry with Fowler scoring of hearing loss, and tinnitus analysis were used to evaluate tinnitus in all patients. Data were recorded the day the patient was included in the study and at 1- and 6-month follow-up. The study groups were...Continue Reading
References
Feb 1, 1989·British Journal of Audiology·A Axelsson, A Ringdahl
Feb 1, 1996·Archives of Otolaryngology--head & Neck Surgery·C W NewmanJ B Spitzer
Jul 15, 2003·Otolaryngologic Clinics of North America·Andrew J Heller
Sep 19, 2003·Hearing Research·A J Noreña, J J Eggermont
Nov 23, 2006·Acta Oto-laryngologica. Supplementum·Robert L FolmerWilliam Hal Martin
Oct 2, 2007·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Tobias KleinjungPeter Eichhammer
Jan 19, 2008·Journal of Neurology, Neurosurgery, and Psychiatry·E M KhedrA El-Atar
Mar 25, 2008·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Tobias KleinjungBerthold Langguth
Nov 14, 2008·PloS One·Winfried SchleeThomas Elbert
Jul 21, 2009·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·R A MarcondesM A Marcolin
Feb 18, 2010·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·G FrankB Langguth
Jan 12, 2011·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·Lindsay ObermanAlvaro Pascual-Leone
Nov 10, 2011·Frontiers in Systems Neuroscience·Peter Michael KreuzerBerthold Langguth
Apr 28, 2012·Neurology·C PlewniaS K Plontke
Aug 3, 2012·Brain Stimulation·Dirk De RidderSven Vanneste
Aug 23, 2012·The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry·B LangguthT Kleinjung
Dec 12, 2012·Brain Topography·Astrid LehnerBerthold Langguth
Jun 21, 2013·Electromagnetic Biology and Medicine·Bo Gyung KimIn Seok Moon
Aug 24, 2013·Trials·Astrid LehnerBerthold Langguth
Oct 26, 2013·Audiology & Neuro-otology·Carlijn E L HoekstraGijsbert A van Zanten
Oct 29, 2013·Neuroscience·L I GevenP van Dijk
Jul 16, 2014·Brain Stimulation·Julien EngelhardtEmmanuel Cuny
Jul 19, 2014·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Jean-Pascal LefaucheurLuis Garcia-Larrea
Mar 24, 2015·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·P M RossiniU Ziemann
Oct 1, 2015·The Laryngoscope·Lauren T RolandJay F Piccirillo
Citations
Aug 23, 2019·Scientific Reports·Stefan SchoisswohlMartin Schecklmann
Jul 21, 2020·Neural Plasticity·Kunkun WangShan Sun
Sep 19, 2020·Brain Topography·Tae-Soo NohMyung-Whan Suh
May 28, 2019·Frontiers in Neuroscience·Yuexin CaiYiqing Zheng
Jul 25, 2019·Frontiers in Neuroscience·Lv HanWang Zhenchang
Jan 5, 2020·Brain Imaging and Behavior·Han LvZhenchang Wang
Nov 25, 2020·BMC Psychiatry·Zhengrong LiangHaiying Jia
Jul 9, 2020·Ear and Hearing·Patricia CiminelliAntonio Egidio Nardi
Dec 5, 2020·Brain Stimulation·Mathilde Lefebvre-DemersShirley Fecteau
Jan 7, 2020·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Jean-Pascal LefaucheurUlf Ziemann
Nov 3, 2020·Brain Communications·Lv HanWang Zhenchang
Mar 18, 2021·The Journal of International Medical Research·Lu YinJuntao Yan
Jun 29, 2021·Frontiers in Aging Neuroscience·Jorge Piano SimoesEleni Genitsaridi