Combined treatment of melasma involving low-fluence Q-switched Nd:YAG laser and fractional microneedling radiofrequency

The Journal of Dermatological Treatment
Hyuck Hoon KwonGyeong-Hun Park

Abstract

Background: While low fluence Q-switched Nd:YAG laser (QSNY) demonstrates moderate efficacy in the melasma treatment for darker skin types, this single regimen still remains challenges. Fractional microneedling radiofrequency (FMR) is known to enhance dermal microenvironment, possibly offsetting pathogenic factors of melasma aggravation. Objectives: To compare the effectiveness and safety of combination therapy using low-fluence QSNY and FRM with QSNY monotherapy in Asian melasma patients Methods: A retrospective study was undertaken for melasma patients to compare clinical data between 56 patients receiving combination regimen and 58 patients with QSNY only. For the 10 sessions at 1-week intervals, combination group was consecutively treated with QSNY and FRM, while QS toning group with QSNY alone. Two blinded dermatologists evaluated the efficacy based on modified Melasma Area and Severity Index (mMASI) and the physician's global assessment (PGA) at baseline and 3 months after the final treatment. Treatment-related side effects and disease course was recorded in detail. Results: Combination group demonstrated better efficacy compared with QS toning only group. Both median degrees of mMASI decrease (2.9 vs. 1.8) and proportion...Continue Reading

References

Jun 1, 1981·Journal of the American Academy of Dermatology·N P SanchezM C Mihm
Mar 21, 2002·The British Journal of Dermatology·W H KangS Im
Sep 27, 2003·The British Journal of Dermatology·R BalkrishnanM-M Chren
Oct 23, 2003·Lasers in Surgery and Medicine·Richard FitzpatrickJavier Ruiz-Esparza
May 18, 2006·The British Journal of Dermatology·H Y KangW H Kang
Mar 20, 2010·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Penpun WattanakraiSasima Eimpunth
Feb 15, 2011·The American Journal of Dermatopathology·Bertha Torres-ÁlvarezBenjamin Moncada
Sep 17, 2011·Journal of the American Academy of Dermatology·Vaneeta M Sheth, Amit G Pandya
Sep 17, 2011·Journal of the American Academy of Dermatology·Vaneeta M Sheth, Amit G Pandya
Oct 18, 2013·Pigment Cell & Melanoma Research·Tae Jun ParkHee Young Kang
Nov 22, 2013·Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)·A TaheriD Pearce
Jan 1, 2014·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Zhenlong ZhengSung Bin Cho
Aug 27, 2014·Journal of the European Academy of Dermatology and Venereology : JEADV·V VejjabhinantaW Manuskiatti
Aug 1, 2015·Pigment Cell & Melanoma Research·Ai-Young Lee
Mar 11, 2016·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Camila Anna Hofbauer ParraLuis Antonio Ribeiro Torezan
May 22, 2016·Journal of the American Academy of Dermatology·Hwee Chyen LeeChee Leok Goh
Jun 2, 2016·BioMed Research International·Woraphong ManuskiattiSorawuth Chu-Ongsakol
Jun 29, 2016·Journal of Cosmetic Dermatology·Hilal GokalpYasemin Oram

❮ Previous
Next ❯

Citations

Jul 23, 2020·Journal of Cosmetic Dermatology·Özlem Karadağ Köse, Murat Borlu
Sep 9, 2020·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Sean Z WuMurad Alam
Mar 6, 2021·Dermatologic Therapy·Behzad IranmaneshMahin Aflatoonian
Feb 13, 2021·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Marcus G TanJeffrey S Dover
Aug 20, 2021·Journal of Cosmetic Dermatology·Ofir ArtziJacob Mashiah
Sep 3, 2021·Lasers in Surgery and Medicine·Iwona MicekJustyna Gornowicz-Porowska

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of Cosmetic and Laser Therapy : Official Publication of the European Society for Laser Dermatology
Chun Pil ChoiJae Eun Choi
Journal of Cosmetic and Laser Therapy : Official Publication of the European Society for Laser Dermatology
Chun Pil ChoiJae Eun Choi
Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]
Camila Anna Hofbauer ParraLuis Antonio Ribeiro Torezan
The Journal of Dermatological Treatment
Ji Hoon SimJung Hoon Lee
© 2022 Meta ULC. All rights reserved