Combined utility of functional MRI, cortical mapping, and frameless stereotaxy in the resection of lesions in eloquent areas of brain in children

Pediatric Neurosurgery
S R StapletonJ T Rutka

Abstract

We studied 16 children with lesions in the eloquent brain to determine if the amalgamation of information from functional magnetic resonance imaging (fMRI), frameless stereotaxy, and direct cortical mapping and recording could facilitate the excision of these lesions while minimizing potential neurological deficits. The mean age of the children was 10 years. Fourteen children presented with seizures. All lesions were located in or near eloquent cerebral cortex. fMRI was successful in all patients in delineating the relationship between the lesion and regions of task-activated cortex. The ISG wand was utilized in all cases for scalp and bone flap placement, and for intraoperative localization of the lesion. Direct cortical stimulation or recording of phase reversals with somatosensory evoked potentials helped delineate the central sulcus and language cortex in patients with lesions near the motor or language cortex. Intraoperative electrocorticography (ECoG) was utilized in all patients who presented with seizures to guide the extent of resection of the epileptiform cortex. Ten children had benign cerebral neoplasms, nine of which were totally resected. The other diagnoses included vascular malformations, Sturge-Weber, tuberous ...Continue Reading

Citations

Jul 19, 2000·Mental Retardation and Developmental Disabilities Research Reviews·M J Rivkin
Sep 12, 2000·Mental Retardation and Developmental Disabilities Research Reviews·W D Gaillard
Nov 26, 2009·Pediatric Radiology·James L Leach, Scott K Holland
May 11, 2004·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Francesco SignorelliJ Isnard
Feb 11, 2010·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Francesco SalaMassimo Gerosa
Nov 16, 2007·Neuropsychology Review·Marla J Hamberger
Mar 20, 2002·Current Neurology and Neuroscience Reports·Lyn M Balsamo, William D Gaillard
Nov 3, 2004·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Gary W ThickbroomFrank L Mastaglia
Dec 18, 2001·Topics in Magnetic Resonance Imaging : TMRI·T Y Poussaint
Jun 1, 2001·Journal of Neurology, Neurosurgery, and Psychiatry·T KringsA Thron
Sep 19, 2001·Journal of Neurology, Neurosurgery, and Psychiatry·F E RouxI Berry
Oct 1, 2004·Developmental Neuropsychology·Rebecca L Billingsley-MarshallAndrew C Papanicolaou
Apr 14, 2009·Journal of Neurosurgery·Hesheng LiuSteven M Stufflebeam
May 4, 2010·Journal of Neurosurgery. Pediatrics·Hillary ShurtleffJeffrey G Ojemann
Sep 2, 2008·Neurosurgical Focus·Scellig S D Stone, James T Rutka
Jan 9, 2001·Journal of Neurosurgery·H W SchroederM R Gaab
May 15, 2003·Journal of Neurosurgery·Cagatay OnalWilliam Logan
Jun 17, 2006·Journal of Neurosurgery·John F Reavey-CantwellDavid W Pincus
Dec 6, 2003·Radiology·Byron Bernal, Nolan R Altman
Feb 23, 2010·Seminars in Roentgenology·Lubdha M ShahRichard Wiggins
Oct 11, 2015·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Petros StylianouSagi Harnof
Jul 11, 2001·Mayo Clinic Proceedings·F B MeyerB P O'Neill
Oct 30, 2007·Neurologic Clinics·Ashok R AsthagiriMark E Shaffrey
Dec 13, 2006·Journal of Neuroscience Methods·Rebecca L Billingsley-MarshallAndrew C Papanicolaou
Jul 13, 2004·Pediatric Neurology·Byron Bernal, Nolan Altman
Aug 16, 2005·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Panagiotis G SimosAndrew C Papanicolaou
Aug 25, 2004·Neuroimaging Clinics of North America·William Davis Gaillard
Jan 10, 2014·Neurosurgery·Bernard R BendokH Hunt Batjer
Jan 19, 2011·Neurosurgery·Man Ning Wang, Zhi Jian Song
Jul 11, 2006·Epilepsia·Dianne P AndersonGraeme D Jackson

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