PMID: 2490399Jan 1, 1989Paper

Combining indirect hemagglutination with the direct agglutination as a parameter for evaluating patients sent for serological verification of toxoplasmosis

Giornale Di Batteriologia, Virologia Ed Immunologia
G MastracchioP Martinetto

Abstract

The importance that Toxoplasma gondii congenital infection may assume is still representing a stimulus for trying to improve Toxoplasmosis serological diagnosis; task, this one, which Laboratory is charged with, and that is often hard, particularly when we have to value the possibility of an infection in progress. With the purpose to complete the results obtained in a preceding work of ours, we have valued two among the most commonly used tests for Toxoplasmosis serodiagnosis, the AD (direct agglutination provided by BioMerieux) and the IHA (indirect haemoagglutination provided by Behring), together and separately, in order to make use of their coupling with major security and effectiveness, on the ground of the results obtained on two different groups of individuals, in the number of 125 for each group; for these groups it was possible to expect a different index of receptivity and a different percentage of recent or in progress infections. It was come out, as regards the IHAm a very good degree of assurance in trying to single out the past immunity, while this test wouldn't generally seem to be able to offer sufficient indications to distinguish the recent or in progress infection from past immunity, as it often declares, in ...Continue Reading

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