Combining tape stripping and non-invasive reflectance confocal microscopy : an in vivo model to study skin damage

Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)
M PeppelmanP E J van Erp

Abstract

Evaluation of (immuno)histological and cell biological changes in damaged skin requires often an invasive skin biopsy, making in vivo models inappropriate to study skin damage. Reflectance confocal microscopy (RCM) might overcome this limitation. Therefore, we evaluated the use of a tape-stripping model in combination with RCM to provide morphological data on skin damage and recovery. In 25 volunteers, a tape-stripping stimulus was applied. The skin was imaged with RCM during 1 week and 3 mm punch biopsies were obtained. Strong correlations between epidermal thickness determined by RCM and conventional histological measurements were found. RCM thickness measurements correlated well with epidermal proliferation. The 10× or 15× repeated tape-stripping resulted in skin damage similar to acute stripping. Mild repeated tape-stripping showed no skin damage. Overall, we demonstrated that non-invasive RCM in combination with tape-stripping could be used as model to obtain morphological and cell biological data on skin-material interactions.

References

Jan 1, 1990·Archives of Dermatological Research·S de MareP C van de Kerkhof
Sep 1, 1987·The Journal of Investigative Dermatology·J N Mansbridge, A M Knapp
Jan 1, 1994·Archives of Dermatological Research·M J GerritsenP C van de Kerkhof
Apr 1, 1995·The Journal of Trauma·D J DalmotasR M Hurley
Jun 1, 1995·The Journal of Investigative Dermatology·M RajadhyakshaR R Anderson
Apr 17, 2001·Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)·S J BashirH I Maibach
May 2, 2002·The Journal of Investigative Dermatology·Robert P ChilcottSimon T Bradley
Nov 27, 2002·Journal of the American Academy of Dermatology·Salvador González, Zeina Tannous
Aug 5, 2006·Journal of Dermatological Science·Ehrhardt ProkschJens-Michael Jensen
Feb 21, 2007·Archives of Dermatology·Alon ScopeAshfaq A Marghoob
Dec 11, 2007·The British Journal of Dermatology·M UlrichS Astner
Sep 9, 2008·European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Für Pharmazeutische Verfahrenstechnik E.V·J LademannJ W Fluhr
Oct 22, 2008·Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)·Kristien De PaepeVera Rogiers
Oct 22, 2008·Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)·Richard I MurahataGary L Grove
Dec 2, 2008·Experimental Dermatology·Ehrhardt ProkschJens-Michael Jensen
Dec 11, 2008·Photochemistry and Photobiology·Piergiacomo Calzavara-PintonGiovanni Pellacani
Feb 27, 2009·Journal of the European Academy of Dermatology and Venereology : JEADV·M ArdigoS González
Mar 27, 2009·Experimental Dermatology·Silvia KollerRainer Hofmann-Wellenhof
Sep 8, 2009·Journal of the European Academy of Dermatology and Venereology : JEADV·E RichtigR Hofmann-Wellenhof
Nov 13, 2009·Dermatology : International Journal for Clinical and Investigative Dermatology·M UlrichS Astner
Apr 14, 2010·Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)·Cristina PadulaPatrizia Santi
Jun 1, 1983·The Journal of Investigative Dermatology·P M Elias
Jan 14, 2011·Journal of the Royal Society, Interface·C Pailler-MatteiS Nicoli
Mar 26, 2011·The American Journal of Pathology·Judith G M BergboerJoost Schalkwijk
Apr 20, 2012·The British Journal of Dermatology·E A W WolberinkM J P Gerritsen
Jan 3, 2013·Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)·Yanrui GaoXiaoping Liu
Feb 14, 2014·Experimental Dermatology·Eshter A W WolberinkMarie-Jeanne P Gerritsen
Mar 8, 2014·Dermatology : International Journal for Clinical and Investigative Dermatology·Anke G M HendriksPeter C M van de Kerkhof
May 1, 2014·Orthopaedic Journal of Sports Medicine·Wilbert A J van den EijndePiet E J van Erp

❮ Previous
Next ❯

Citations

Aug 8, 2015·BioMed Research International·Hinda DabboueGilberte Marti-Mestres
Jul 7, 2016·Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)·F M W RodijkM Peppelman
Oct 27, 2016·Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)·Y-F MaP Humbert
Nov 2, 2016·Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)·D FalconeP E J van Erp
Jul 19, 2018·Experimental Dermatology·Piet E J van ErpDenise Falcone
Feb 6, 2020·Annals of Work Exposures and Health·Wilbert van den EijndePiet van Erp
Mar 20, 2020·The Journal of Dermatological Treatment·Jade G M LoggerRieke J B Driessen
Aug 23, 2019·Scientific Reports·Caroline Meyer OlesenMaja-Lisa Clausen
Jul 16, 2017·Dermatology and Therapy·Hanan Osman-PonchetClaire E Wilson

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of the American Academy of Dermatology
Anna Liza Chan AgeroAllan C Halpern
Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)
Y K BaşaranI S Bağci
Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)
Yanrui GaoXiaoping Liu
© 2021 Meta ULC. All rights reserved