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Comment on “TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions” by Kim et al.

bioRxiv

Nov 22, 2013

Alexander Dobin, Thomas R Gingeras

Abstract

In the recent paper [[1][1]] (thereafter referred to as “TopHat2paper”) the accuracy of TopHat2 was compared to other RNA-seq aligners. In this comment we re-examine most important analyses from the TopHat2paper and identify several deficiencies that significantly diminished performance...read more

Mentioned in this Paper

Chimera Organism
Gene Deletion
Bio-Informatics
Vitamin D Deficiency
Analysis
Transcriptome
Metric
Gene Insertion
RNA
Gene Fusion
37
9
Paper Details
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Comment on “TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions” by Kim et al.

bioRxiv

Nov 22, 2013

Alexander Dobin, Thomas R Gingeras

PMID: 990000851

DOI: 10.1101/000851

Abstract

In the recent paper [[1][1]] (thereafter referred to as “TopHat2paper”) the accuracy of TopHat2 was compared to other RNA-seq aligners. In this comment we re-examine most important analyses from the TopHat2paper and identify several deficiencies that significantly diminished performance...read more

Mentioned in this Paper

Chimera Organism
Gene Deletion
Bio-Informatics
Vitamin D Deficiency
Analysis
Transcriptome
Metric
Gene Insertion
RNA
Gene Fusion
37
9
Paper Details
References
  • References
  • Citations
  • finger pointing at paper

    References currently unavailable

    We're still populating references for this paper, please check back later.
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