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Comment on “TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions” by Kim et al.

bioRxiv

Nov 22, 2013

Alexander Dobin, Thomas R. Gingeras

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Abstract

In the recent paper by Kim et al. (Genome biology, 2013. 14(4): p. R36) the accuracy of TopHat2 was compared to other RNA-seq aligners. In this comment we re-examine most important analyses from this paper and identify several deficiencies that significantly diminished performance of so...read more

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  • Comment on “TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions” by Kim et al.

    bioRxiv

    Nov 22, 2013

    Alexander Dobin, Thomas R. Gingeras

    PMID: 990000851

    DOI: 10.1101/000851

    Abstract

    In the recent paper by Kim et al. (Genome biology, 2013. 14(4): p. R36) the accuracy of TopHat2 was compared to other RNA-seq aligners. In this comment we re-examine most important analyses from this paper and identify several deficiencies that significantly diminished performance of so...read more

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    9
    Paper Details
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