Commentary--the proteomics: a new tool for Chinese medicine research

The American Journal of Chinese Medicine
Shi-Sheng Li

Abstract

Proteomics technology is based on the vast analytical power for protein/peptide identification and quantification offered by modern mass spectrometry coupled with hyphenated separation techniques such as two-dimensional gel electrophoresis (2DE) and micro- or nano-scale multidimensional liquid chromatography. The rapid growth of proteomics field provides an array of new tools for the integration of traditional Chinese medicine (TCM) with modern technology and systems biology, and is potentially advancing the progress of modernization and internationalization of TCM. Cho, in this issue of the American Journal of Chinese Medicine, highlights the recent application of 2DE-based and bottom-up proteomics in Chinese medicine research, including the exploration of pharmacological mechanisms of the actions of TCM, the facilitation of herb authentication and identification, and the profiling of protein expression following acupuncture treatment in animal models. Recent development in proteomics has provided further refinement on the analysis of proteins posttranslational modifications as well as quantitative comparison of different proteomes, and enabled the study of proteomes of specific diseases or biological processes under clinicall...Continue Reading

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Citations

Dec 16, 2010·Chinese Medicine·Halil UzunerQihe Xu
Mar 18, 2010·British Journal of Pharmacology·Zhi-Ping Zeng, Jian-Guo Jiang
Dec 12, 2012·The American Journal of Chinese Medicine·Xijun WangPing Wang
Mar 3, 2017·Evidence-based Complementary and Alternative Medicine : ECAM·Dalinda Isabel Sánchez-VidañaMan-Sau Wong
May 22, 2009·Current Opinion in Obstetrics & Gynecology

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