Comments on the discordant recommendations for the use of symptomatic slow-acting drugs in knee osteoarthritis

Current Medical Research and Opinion
Jean-Yves ReginsterO Bruyère

Abstract

Despite the near concurrent publication by influential scientific organizations, there are important differences in interpretation of the evidence base and the conclusions derived from the recent Osteoarthritis Research Society International (OARSI) guidelines for the management of knee osteoarthritis, the American College of Rheumatology (ACR) guidelines (concerning also hip and hand osteoarthritis) and the algorithm recommendations by the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO). This is particularly evident for the drug class of symptomatic slow-acting drugs in osteoarthritis. In this paper, we highlight these differences and try to understand where they derive from, proposing an evidence-based interpretation.

References

Feb 24, 2006·The New England Journal of Medicine·Daniel O CleggH James Williams
Apr 18, 2007·Annals of Internal Medicine·Stephan ReichenbachPeter Jüni
Jun 23, 2009·Rheumatology International·Young Ho LeeGwan Gyu Song
Jul 1, 2009·Expert Review of Clinical Pharmacology·Roy D Altman
Aug 8, 2012·Annals of Internal Medicine·Anne W S RutjesStephan Reichenbach
Sep 12, 2012·Nature Reviews. Rheumatology·Timothy E McAlindon, Raveendhara R Bannuru
Jan 28, 2014·Osteoarthritis and Cartilage·T E McAlindonM Underwood

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Citations

Feb 17, 2018·Expert Opinion on Pharmacotherapy·Olivier Bruyère
Jun 28, 2019·Aging Clinical and Experimental Research·Germain HonvoJean-Yves Reginster
Oct 19, 2019·Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova·A V NaumovO N Tkacheva

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