Abstract
In this study we systematically reviewed outcomes in recipients and donors of commercial kidney transplants. Inherent in a study of this nature is the possibility of center and country bias, in particular there are no publications from China and South America. Publications also tended to report poor outcomes which may reflect bias on the part of the authors or to highlight the ethical issues in this area. We were unable to perform a meta-analysis due to variability in studies making it impossible to synthesize the data other than descriptive. Furthermore, these studies were not large or well conducted. We found that patient and graft survival was generally inferior to the data obtained from the UNOS (United Network for Organ Sharing). Some studies did achieve good outcomes, however, due to lack of details, it was not possible to infer if the donor hospital, surgical technique or immunosuppressive regimen was a factor. There was a higher incidence of unconventional and life-threatening infections such as malaria, invasive fungal infections, pneumonia, HIV and hepatitis. There was also a markedly increased incidence of postoperative surgical interventions in recipients. We suggest the establishment of a database for both recipien...Continue Reading
Citations
Aug 15, 2013·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Lin H Chen, Mary E Wilson
Nov 26, 2010·Nephrology·Chih-Cheng HsuKen N Kuo
Jun 2, 2012·Journal of Transplantation·Frederike AmbagtsheerWillem Weimar
Mar 13, 2012·Annals of African Medicine·Bappa AdamuFuad Alshaebi
Jan 29, 2011·Kidney International·Meng-Kun TsaiPo-Huang Lee
Nov 26, 2009·Health Policy·Roger Lee Mendoza
Apr 17, 2016·Kidney International·G V Ramesh PrasadJeffrey S Zaltzman
Feb 12, 2009·Transplant International : Official Journal of the European Society for Organ Transplantation·Syed Adibul Hasan RizviEjaz Ahmed
Apr 11, 2012·Clinical Transplantation·Ashley E Anker, Thomas H Feeley
Jul 27, 2012·Transplant International : Official Journal of the European Society for Organ Transplantation·Allison TongJonathan C Craig
Apr 16, 2015·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·F AmbagtsheerW Weimar
Apr 15, 2015·Current Infectious Disease Reports·Jennifer M Babik, Peter Chin-Hong
Sep 18, 2014·The American Journal of Bioethics : AJOB·Julian Koplin
Sep 17, 2016·Progress in Transplantation : Official Publication, North American Transplant Coordinators Organization ... [et Al.]·L J van BalenW Weimar
Feb 24, 2012·World Journal of Transplantation·Jacob A Akoh
Oct 17, 2017·Nephrology·Meteb M AlBugamiKhalid Bel'eed-Akkari
Dec 30, 2014·Medicine·Mu-Chi ChungChi-Jung Chung
Nov 3, 2017·Transplantation·Rahul M Jindal
Oct 12, 2017·Transplantation·Beatriz Domínguez-GilUNKNOWN Declaration of Istanbul Custodian Group working group on ethical travel for transplantation.
May 27, 2009·Current Opinion in Organ Transplantation·Benita S Padilla
May 27, 2009·Current Opinion in Organ Transplantation·Adibul Hasan S RizviEjaz Ahmed
Mar 25, 2009·Current Opinion in Organ Transplantation·Miran Epstein
Mar 25, 2009·Current Opinion in Organ Transplantation
Nov 6, 2009·Current Opinion in Supportive and Palliative Care