PMID: 561291May 1, 1977

Common action of limiting and inhibiting factors on the growth of yeasts in a continuous culture

Mikrobiologiia
A N Shkidchenko

Abstract

Candida utilis was cultivated under conditions of chemostat and continuous growth which was limited by phosphates. An excess of glucose inhibited the growth. The limiting and inhibiting factors produced simultaneous cooperative action. At a constant velocity of the medium flow, the concentration of biomass decreased, as a result of the inhibition of growth with residual glucose (0.96 and 1.36 per cent), by 5.5 and 15.6 per cent of the absolute value, respectively. The economic coefficient decreased in this case from 40 to 28 per cent. The inhibition of yeast growth resulted also in a decrease of phosphorus content in the cells; moreover, the cells could not utilize all oxygen dissolved in the medium.

Related Concepts

Candida utilis
Drug Augmentation
Glucose, (beta-D)-Isomer
Orthophosphate

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