Common Amino Acid Subsequences in a Universal Proteome--Relevance for Food Science

International Journal of Molecular Sciences
P MinkiewiczMonika Hrynkiewicz

Abstract

A common subsequence is a fragment of the amino acid chain that occurs in more than one protein. Common subsequences may be an object of interest for food scientists as biologically active peptides, epitopes, and/or protein markers that are used in comparative proteomics. An individual bioactive fragment, in particular the shortest fragment containing two or three amino acid residues, may occur in many protein sequences. An individual linear epitope may also be present in multiple sequences of precursor proteins. Although recent recommendations for prediction of allergenicity and cross-reactivity include not only sequence identity, but also similarities in secondary and tertiary structures surrounding the common fragment, local sequence identity may be used to screen protein sequence databases for potential allergens in silico. The main weakness of the screening process is that it overlooks allergens and cross-reactivity cases without identical fragments corresponding to linear epitopes. A single peptide may also serve as a marker of a group of allergens that belong to the same family and, possibly, reveal cross-reactivity. This review article discusses the benefits for food scientists that follow from the common subsequences c...Continue Reading

References

Jan 1, 1981·Reviews of Infectious Diseases·H Mattie
Dec 1, 1994·Bioscience, Biotechnology, and Biochemistry·H MatsufujiY Osajima
Sep 1, 1997·Nucleic Acids Research·S F AltschulD J Lipman
Jun 30, 1998·FEBS Letters·A A KarelinV T Ivanov
Nov 28, 2002·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·C Bindslev-JensenL K Poulsen
May 29, 2003·Journal of Agricultural and Food Chemistry·Koichiro SaitoKiyoshi Nokihara
Dec 19, 2003·Nucleic Acids Research·Alex BatemanSean R Eddy
Feb 26, 2004·Allergy·F FerreiraA Mari
Feb 6, 2007·Immunology and Allergy Clinics of North America·Catherine H ScheinWerner Braun
Apr 14, 2007·Current Pharmaceutical Design·Yoshinori Mine
May 4, 2007·Journal of Agricultural and Food Chemistry·Hubert ChassaigneArjon J van Hengel
Aug 7, 2007·BMC Bioinformatics·Timur ShtatlandRalph Weissleder
Sep 4, 2007·The British Journal of Nutrition·Caroline BauchartDidier Rémond
Oct 12, 2007·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·V DevesaR Montoro
Jan 29, 2008·Current Pharmaceutical Design·D Kanduc
Apr 9, 2008·The Journal of Allergy and Clinical Immunology·Christian RadauerHeimo Breiteneder
Apr 19, 2008·Amino Acids·Zhi-Ping LiuLuonan Chen
Jan 27, 2009·Journal of Proteomics·Andrej ShevchenkoMagno Junqueira
Apr 29, 2009·Current Opinion in Structural Biology·Benoît H DessaillyChristine A Orengo
Jun 23, 2009·Proceedings of the National Academy of Sciences of the United States of America·Michael Levitt
Jul 14, 2009·Peptides·Anthony KusalikDarja Kanduc
Jul 15, 2009·The Journal of Allergy and Clinical Immunology·Melanie AlbrechtStefan Vieths
Aug 13, 2009·Current Allergy and Asthma Reports·Adriano MariEnrico Scala
Oct 12, 2010·Journal of Agricultural and Food Chemistry·Huan Li, Rotimi E Aluko
Feb 22, 2011·Journal of Food Protection·Christiane Kruse FæstePer Einar Granum
Mar 3, 2011·Food Science and Technology International = Ciencia Y Tecnología De Los Alimentos Internacional·P MinkiewiczJ Michalska
Jul 26, 2011·Database : the Journal of Biological Databases and Curation·Philip JonesSarah Hunter
Jul 29, 2011·Critical Reviews in Food Science and Nutrition·Janitha P D Wanasundara
Oct 11, 2011·Journal of Cheminformatics·Noel M O'BoyleGeoffrey R Hutchison
Mar 7, 2012·Cardiovascular Drugs and Therapy·Michel Azizi, Joël Ménard
Apr 26, 2012·Bioinformatics·Joshua TanSebastian Maurer-Stroh
Jun 15, 2012·Journal of Peptide Science : an Official Publication of the European Peptide Society·Darja Kanduc
Sep 29, 2012·ACS Chemical Neuroscience·Jean-Louis Reymond, Mahendra Awale

❮ Previous
Next ❯

Citations

Apr 5, 2016·International Journal of Molecular Sciences·Lakshmi A DaveShane M Rutherfurd
Feb 2, 2018·Critical Reviews in Food Science and Nutrition·Domancar Orona-TamayoOctavio Paredes-López
Dec 1, 2019·International Journal of Molecular Sciences·Piotr MinkiewiczMałgorzata Darewicz
Jan 20, 2018·PloS One·Agustina E NardoGustavo Parisi
Jan 21, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Vasso ApostolopoulosIstvan Toth

❮ Previous
Next ❯

Methods Mentioned

BETA
electrophoresis

Software Mentioned

ChEMBL
InChIKey
PubChem
BIOPEP
ChemSpider
Tachyon
InChI
BLAST
SMILES
InChIKeys

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology
Patrizia RestaniCorrado L Galli
Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology
Rob C Aalberse, S O Stapel
© 2021 Meta ULC. All rights reserved