Common and uncommon variants of melanocytic naevi

Pathology
Inara Strungs

Abstract

Numerous variants of melanocytic naevi have been described. Their main pathological significance lies in their distinction from melanoma, as well as being precursors and risk markers for melanoma. Various degrees of atypia such as cytological atypia, architectural disorder and pagetoid spread (pagetoid melanocytosis) may be present in naevi and need to be recognised as appropriate for the subtype. As well as the distinction from melanoma, naevi must be differentiated from atypical lesions, such as atypical Spitz tumours, which do not fulfil all the criteria of melanoma, may be benign or malignant and have been called 'melanocytic tumours of unknown malignant potential'. The diagnostic grey area also includes a group of benign atypical naevi which are difficult to subclassify into specific entities. In this paper naevi are divided into: firstly, the common acquired group with a brief discussion of junctional, compound and intradermal naevi, minor variants such as halo and balloon naevi and the major variants that may cause problems -- dysplastic naevi, naevi of special sites, recurrent naevi and Spitz naevi; secondly, congenital naevi; thirdly, blue naevi and related lesions (dermal melanocytoses); and finally, combined naevi. T...Continue Reading

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Citations

Jul 28, 2010·The American Journal of Dermatopathology·Katharina GlatzHeinz Kutzner
May 30, 2012·Pediatric Dermatology·Mónica P Novoa-CandiaFrancesc Tresserra
Apr 24, 2007·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·Yi-Shing Lisa ChengStephen Watson
Aug 14, 2009·Journal of Cutaneous Pathology·Dara N WakefieldKlaus Sellheyer
Nov 1, 2013·Journal of the European Academy of Dermatology and Venereology : JEADV·A Larre BorgesE Moscarella
Dec 18, 2007·Seminars in Oncology·Meenhard HerlynDaniel Pinkel
Jul 18, 2015·Journal of the American Academy of Dermatology·Amir ZahirSabrina Newman
Apr 14, 2015·The Journal of Pediatrics·Laura B CampbellJeremy S Bordeaux
Oct 21, 2016·Journal of Cutaneous Pathology·Anthony P FernandezMelissa P Piliang
Sep 29, 2020·Pediatric Dermatology·Giuseppe MicaliFrancesco Lacarrubba

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