Common data elements for predictors of pediatric sepsis: A framework to standardize data collection.

PloS One
Alishah MawjiMark Ansermino

Abstract

Standardized collection of predictors of pediatric sepsis has enormous potential to increase data compatibility across research studies. The Pediatric Sepsis Predictor Standardization Working Group collaborated to define common data elements for pediatric sepsis predictors at the point of triage to serve as a standardized framework for data collection in resource-limited settings. A preliminary list of pediatric sepsis predictor variables was compiled through a systematic literature review and examination of global guideline documents. A 5-round modified Delphi that involved independent voting and active group discussions was conducted to select, standardize, and prioritize predictors. Considerations included the perceived predictive value of the candidate predictor at the point of triage, intra- and inter-rater measurement reliability, and the amount of time and material resources required to reliably collect the predictor in resource-limited settings. We generated 116 common data elements for implementation in future studies. Each common data element includes a standardized prompt, suggested response values, and prioritization as tier 1 (essential), tier 2 (important), or tier 3 (exploratory). Branching logic was added to the...Continue Reading

References

Jul 22, 2009·PLoS Medicine·David MoherUNKNOWN PRISMA Group
Feb 22, 2012·Intensive Care Medicine·Martin W DünserUNKNOWN Global Intensive Care Working Group of European Society of Intensive Care Medicine
Mar 1, 2012·Clinical Trials : Journal of the Society for Clinical Trials·Stacie T GrinnonSelma Kunitz
Jan 29, 2013·Critical Care Medicine·R Phillip DellingerUNKNOWN Surviving Sepsis Campaign Guidelines Committee including the Pediatric Subgroup
Feb 24, 2016·JAMA : the Journal of the American Medical Association·Mervyn SingerDerek C Angus
Jun 18, 2016·Clinical Trials : Journal of the Society for Clinical Trials·Jerry SheehanMichael Huerta

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