Common psychiatric comorbidities in epilepsy: How big of a problem is it?

Epilepsy & Behavior : E&B
Jay A Salpekar, Marco Mula

Abstract

Psychiatric illness and epilepsy commonly co-occur in adults and in children and adolescents. Theories of comorbidity are complex, but recurring associations between the conditions suggest overlap that is more than simple co-occurrence. Common underlying pathophysiology may imply that epilepsy itself may constituently include psychiatric symptoms. Conditions such as depression or cognitive difficulties commonly occur and in some cases, are considered to be associated with specific epilepsy characteristics such as localization or seizure type. Regardless of etiologic attributions to psychiatric comorbidity, it is clear today that treatment for epilepsy needs to target psychiatric illness. In many cases, quality-of-life improvements depend more upon addressing psychiatric symptoms than seizures themselves.

Citations

Sep 25, 2019·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·T J O'DonohoeE Callander
Sep 6, 2019·Neurotherapeutics : the Journal of the American Society for Experimental NeuroTherapeutics·Krzysztof KamińskiPiotr Wlaź
Jul 7, 2020·Epilepsy Currents·Phillip L W Colmers, Jamie Maguire
Jul 14, 2020·BJPsych Open·Marco Mula, Kenneth R Kaufman
Jan 30, 2020·Frontiers in Cellular Neuroscience·Karen M J van Loo, Albert J Becker
Aug 28, 2020·Frontiers in Pharmacology·Denise Dias de OliveiraRenê O Beleboni
Nov 29, 2020·Epilepsy & Behavior : E&B·Benzi M KlugerMark Spitz
Jan 21, 2021·BMC Health Services Research·Muhammad Arif AsgharMuhammad Asif Asghar
Jan 15, 2021·Epilepsy & Behavior : E&B·E Justine RecordWilliam D Gaillard
Aug 1, 2020·Translational Psychiatry·Luca SteardoAlexei Verkhratsky
Feb 21, 2021·Epilepsy & Behavior : E&B·Abigail ShegelmanMackenzie C Cervenka
Mar 23, 2021·Acta Neurologica Scandinavica·Aglaia VignoliMaria Paola Canevini
Jul 13, 2021·Experimental and Therapeutic Medicine·Raluca Simona GurguCristina Aura Panea

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