Commonly performed procedures in clinical research: a benchmark for payment.

Contemporary Clinical Trials
Dinora DominguezChristine Grady

Abstract

Slow or insufficient enrollment in clinical research and a high demand for research participants raises questions about the need for and use of incentives to participate, including payment. Much of the available literature on payment to research participants focuses on ethical concerns, and rarely addresses guidelines, benchmarks, or formulas to assist investigators to assign or evaluate appropriate payment for individuals who take part in clinical research trials and procedures. Using four years of data collected about the inconvenience units assigned by intramural investigators to selected clinical research procedures conducted at the National Institutes of Health (NIH) Clinical Center, this study provides payment benchmarks for commonly performed procedures. Results were obtained from data collected on 36,273 incidents of payment made for procedures to research participants from August 2004 to August 2008. Analysis of the inconvenience units value assigned to specific procedures suggests that despite a wide distribution and frequent outliers, a convergence in practice around the center of distribution for most procedures does exist. As one of the first published studies reporting data reflecting payment amount for specific c...Continue Reading

References

Mar 5, 2002·Annals of Internal Medicine·Neal DickertChristine Grady
Mar 14, 2003·JAMA : the Journal of the American Medical Association·Nancy S SungDavid Rimoin
May 25, 2005·Contemporary Clinical Trials·Christine GradyEzekiel Emanuel
Apr 3, 2007·Contemporary Clinical Trials·Andrew L Avins, Harley Goldberg
Dec 1, 2007·Journal of Empirical Research on Human Research Ethics : JERHRE·Robert KlitzmanPaul S Appelbaum
Nov 21, 2009·Social Science & Medicine·Cynthia E CryderGeorge Loewenstein
Sep 14, 2010·Journal of Empirical Research on Human Research Ethics : JERHRE·Elizabeth RipleyChris Gennings
Dec 15, 2010·Contemporary Clinical Trials·Leanne Stunkel, Christine Grady
Sep 21, 2011·Journal of Empirical Research on Human Research Ethics : JERHRE·Carmen Radecki BreitkopfSusan L Rosenthal

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Citations

Jun 1, 2015·The Lancet Infectious Diseases·Thomas C DartonAndrew J Pollard
Sep 14, 2018·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Karen M WinkfieldBeverly Moy
Mar 6, 2018·Health Education & Behavior : the Official Publication of the Society for Public Health Education·Alyssa T BrooksGwenyth R Wallen
Sep 24, 2019·The American Journal of Bioethics : AJOB·Emily E Anderson
Jul 22, 2017·Evaluation & the Health Professions·Yubraj AcharyaJulie C Lumeng
Feb 22, 2018·The New England Journal of Medicine·Luke GelinasHolly Fernandez Lynch
Feb 18, 2020·Clinical Trials : Journal of the Society for Clinical Trials·Luke GelinasBarbara E Bierer
May 2, 2018·Therapeutic Innovation & Regulatory Science·Emily Anderson, Lindsay McNair
Oct 14, 2020·Human Reproduction·Guido Pennings
Feb 23, 2021·The American Journal of Bioethics : AJOB·Emily E Anderson, Brandon Brown

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