Community-based Outcomes of Open versus Robot-assisted Radical Prostatectomy

European Urology
Annika HerlemannMatthew R Cooperberg

Abstract

Identifying the optimal surgical approach for patients with localized prostate cancer (PCa) managed in the community setting remains controversial due to the lack of robust, prospective data. To assess surgical outcomes and changes in urinary and sexual quality of life (QOL) over time in patients undergoing radical prostatectomy (RP). Our study included patients enrolled in Cancer of the Prostate Strategic Urologic Research Endeavor (CaPSURE), a large, prospective, mostly community-based, nationwide PCa registry, who underwent RP between 2004 and 2016. Open (ORP) versus robot-assisted radical prostatectomy (RARP) for localized PCa. Demographic and clinicopathologic data and surgical outcomes were compared between ORP and RARP. Self-reported, validated questionnaires (scaled 0-100 with higher numbers indicating better function) were used to evaluate urinary and sexual QOL at different time points. Repeated measures mixed-models assessed changes in function and bother over time in each domain. Among 1892 men (n = 1137 ORP; n = 755 RARP), Cancer of the Prostate Risk Assessment score, Gleason grade at biopsy and RP, and pT-stage were lower in ORP patients (all p < 0.01). Men undergoing RARP had comparable surgical margin rates, lym...Continue Reading

Citations

Mar 23, 2018·Neurourology and Urodynamics·Markus GrabbertRicarda M Bauer
Apr 6, 2019·Annals of Surgical Oncology·John T MiuraJonathan S Zager
Aug 23, 2019·Japanese Journal of Clinical Oncology·Katsuyoshi HashineMasafumi Matsumura
May 31, 2019·Minerva urologica e nefrologica = The Italian journal of urology and nephrology·Marco RoscignoLuigi F Da Pozzo
Jun 22, 2020·Journal of Clinical Monitoring and Computing·Stefanie BeckMarlene Fischer
Nov 6, 2020·The World Journal of Men's Health·Nicolò SchifanoAndrea Salonia
Jun 19, 2021·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·Melanie M A LindenbergWim W H van Harten

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