Community-based study in Taiwan aborigines concerning renal dysfunction in gout patients

Scandinavian Journal of Rheumatology
S J ChangY C Ko

Abstract

To reveal the factors associated with renal dysfunction among gout patients in Taiwan aborigines. Social demographic data, alcohol consumption data, anthropometric measurements, blood samples, and 24-h urine samples were collected from 128 aboriginals (101 men, 27 women) suffering from gout. The men displayed higher mean creatinine clearance (Ccr) values than women. Twenty-two post-menopausal women had significantly lower Ccr values compared to the five pre-menopausal women [probability (p)<0.001]. The males displayed higher 24-h urinary creatinine value than females (8.60+/-5.39 versus 5.58+/-2.14 mmol/L; p<0.05), and showed a significantly higher positive relationship between 24-h urinary creatinine and uric acid excretion [correlation coefficient (r)=0.7304; p<0.001], whereas the females did not (r=0.1144; p=0.5691). Overall, those who were older members of the Tsou tribe, or had excreted less uric acid from urine in 24 h tended to suffer renal dysfunction. Gout patients displayed diversity in renal function. An exogenous source of creatinine in men was more likely than in women.

References

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Citations

Jan 20, 2010·Clinical Rheumatology·K J M Jansen Dirken-HeukensfeldtA L M Lagro-Janssen
Apr 10, 2013·International Journal of Epidemiology·Albert Min-Shan KoYing-Chin Ko
Jul 27, 2012·Journal of Clinical Rheumatology : Practical Reports on Rheumatic & Musculoskeletal Diseases·Sergio García-MéndezJanitzia Vázquez-Mellado

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