PMID: 9629949Jun 18, 1998Paper

Comorbid depressive disorder increases vulnerability to the 35% carbon dioxide (CO2) challenge in panic disorder patients

Journal of Affective Disorders
K VerburgE Griez

Abstract

The hypothesis of this study was that panic disorder patients with a comorbid depressive disorder would be less vulnerable to the 35% CO2 panic provocation challenge than panic disorder patients without a comorbid depressive disorder. This hypothesis was based on findings from ventilatory response studies in depressive patients. Twelve panic disorder patients with and 23 panic disorder patients without a comorbid depressive disorder were challenged. Panic disorder patients with a comorbid depressive disorder scored significantly higher on ratings of subjective anxiety and panic symptoms induced by the challenge. A comorbid depressive disorder appeared to increase the vulnerability of panic disorder patients to this panic provocation. We did find significant differences, but these differences did not confirm the original hypothesis. Our results support clinical data that show that a comorbid depressive disorder correlates with an increased severity of panic disorder.

References

Jan 1, 1978·Journal of Psychosomatic Research·J Damas-MoraW D Addis
Jul 1, 1976·Psychosomatic Medicine·J C ShershowH Kazemi
Oct 1, 1991·Psychiatry Research·J ZandbergenE J Griez
Apr 1, 1990·Biological Psychiatry·W C Sanderson, S Wetzler
Jul 1, 1985·The American Journal of Psychiatry·A BreierG R Heninger
Feb 1, 1987·Psychiatry Research·E J GriezG M van der Molen
Feb 1, 1988·Acta Psychiatrica Scandinavica·H LousbergM A van den Hout
Mar 1, 1973·Psychosomatic Medicine·J C ShershowS Robinson
Jul 1, 1984·The American Journal of Psychiatry·J M GormanD F Klein
Dec 1, 1984·Archives of General Psychiatry·A BreierG R Heninger
Feb 21, 1995·Journal of Affective Disorders·K VerburgH Pols
Mar 14, 1995·Journal of Affective Disorders·G PernaM Gasperini
Dec 1, 1994·Acta Psychiatrica Scandinavica·C VerburgJ Meijer
May 1, 1994·Psychiatry Research·G PernaL Bellodi
Jul 1, 1994·Behaviour Research and Therapy·P SpinhovenA J Van der Does
Nov 1, 1996·The Journal of Clinical Psychiatry·H J PolsE J Griez
Jul 10, 1998·Psychiatry Research·K VerburgE Griez

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Citations

Dec 22, 1998·Journal of Psychosomatic Research·E Griez, K Schruers
Apr 1, 2004·Acta Neuropsychiatrica·K R J SchruersE Griez
Oct 22, 2013·Revista brasileira de psiquiatria : orgão oficial da Associação Brasileira de Psiquiatria, Asociación Psiquiátrica de la América Latina·Julio Mario Xerfan do AmaralAntonio Egidio Nardi
Apr 16, 2005·Canadian Journal of Psychiatry. Revue Canadienne De Psychiatrie·Thea OverbeekEric Griez

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