Comorbid social anxiety disorder in patients with alcohol use disorder: A systematic review

Journal of Psychiatric Research
Lucas Mendes OliveiraIves Cavalcante Passos

Abstract

Lifetime prevalence of social anxiety disorder (SAD) among patients with alcohol dependence is around 11%. However, no systematic review has assessed the effect of comorbid SAD on the clinical outcomes of patients with alcohol use disorder (AUD). We aimed to compare clinical outcomes, such as alcohol relapse, suicide attempts, treatment response, readmissions, psychiatric comorbidities, and treatment compliance between patients with AUD and comorbid SAD versus patients with AUD without SAD. We carried out a systematic review by searching PubMed for articles published between January 1, 1960 and May 6, 2018. Inclusion criteria were met if a study reported a dichotomous sample of adult patients with AUD and SAD compared to patients with AUD without SAD. Review articles and preclinical studies were excluded. From the eligible studies, we extracted outcomes of interest, such as alcohol relapse, suicidal thoughts, suicide plan and attempts, treatment response, readmissions, psychiatric comorbidities, and treatment compliance. Patients with both AUD and SAD have a higher prevalence of psychiatric comorbidities, mainly major depressive disorder (MDD), and depressive symptoms. In addition, they have poor treatment compliance. Conversel...Continue Reading

Citations

Mar 23, 2019·International Journal of Molecular Sciences·Iulia Zoicas, Johannes Kornhuber
Apr 24, 2019·Addiction Biology·Phillip StarskiDoo-Sup Choi
Nov 14, 2019·International Journal of Molecular Sciences·Iulia Zoicas, Johannes Kornhuber
Mar 27, 2020·Frontiers in Behavioral Neuroscience·Roberto Sebastián Miranda-MoralesJuan Carlos Molina
Nov 6, 2020·Alcoholism, Clinical and Experimental Research·Vanessa A PalzesStacy A Sterling
Aug 26, 2021·Alcoholism, Clinical and Experimental Research·Benjamin L ThompsonMarlene Oscar-Berman

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