Comorbidities and COPD severity in a clinic-based cohort

BMC Pulmonary Medicine
Chantal RaherisonMathieu Molimard

Abstract

Chronic obstructive pulmonary disease (COPD) is an important cause of morbidity and mortality around the world. The aim of our study was to determine the association between specific comorbidities and COPD severity. Pulmonologists included patients with COPD using a web-site questionnaire. Diagnosis of COPD was made using spirometry post-bronchodilator FEV1/FVC < 70%. The questionnaire included the following domains: demographic criteria, clinical symptoms, functional tests, comorbidities and therapeutic management. COPD severity was classified according to GOLD 2011. First we performed a principal component analysis and a non-hierarchical cluster analysis to describe the cluster of comorbidities. One thousand, five hundred and eighty-four patients were included in the cohort during the first 2 years. The distribution of COPD severity was: 27.4% in group A, 24.7% in group B, 11.2% in group C, and 36.6% in group D. The mean age was 66.5 (sd: 11), with 35% of women. Management of COPD differed according to the comorbidities, with the same level of severity. Only 28.4% of patients had no comorbidities associated with COPD. The proportion of patients with two comorbidities was significantly higher (p < 0.001) in GOLD B (50.4%) and ...Continue Reading

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Citations

Nov 27, 2019·Behavioral Sciences·Marina Sánchez-Rico, Jesús M Alvarado
Nov 27, 2020·Respiratory Research·M ZysmanC Raherison-Semjen
Apr 20, 2021·Physiotherapy Theory and Practice·Nnamdi MgbemenaAnthony S Leicht
Apr 29, 2021·International Journal of Chronic Obstructive Pulmonary Disease·Nirupama PutchaSanjay Sharma
Jul 3, 2021·International Journal of Molecular Sciences·Stanislav Kotlyarov, Anna Kotlyarova
Oct 9, 2021·NPJ Primary Care Respiratory Medicine·Donald P TashkinShahin Sanjar

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