Comorbidities and male infertility: a worrisome picture

Current Opinion in Urology
Eugenio VentimigliaAndrea Salonia

Abstract

The purpose of this review is to analyze the current literature concerning health status in the setting of male infertility, taking into account the potential contribution of each comorbidity. Latest findings, almost unanimously confirmed how infertile patients usually display a quite precarious health, because of the collection of coexistent diseases observed in these men. More precisely, relevant comorbidities might influence not only man's fertility but his life expectancy as well. Moreover, because of the increasing trend in delaying fatherhood observed in Western countries over time, age might somehow act as a possible detrimental factor. Overall, what emerges from these studies is a complex and worrisome scenario. General health status in the male reproductive setting is gaining increasing clinical attention and relevance. Infertile men appear to be rather unhealthy young men as compared with fertile ones. Therefore, uroandrologists are challenged with the compelling task of assessing the infertile man considering both his general and his reproductive health, since relevant comorbid conditions may influence not only his life expectancy, but his fertility as well.

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Citations

Mar 24, 2017·Human Fertility : Journal of the British Fertility Society·Eleanor L Stevenson, Kevin R McEleny
Oct 14, 2017·Multiple Sclerosis : Clinical and Laboratory Research·Clara Helene GlazerJens Peter Bonde
May 10, 2017·Human Reproduction·Clara Helene GlazerElvira Vaclavik Bräuner
Aug 16, 2019·Journal of Translational Medicine·Federica CariatiRossella Tomaiuolo
Dec 16, 2020·Epigenomics·Oladele A OluwayioseJ Richard Pilsner
May 10, 2021·Current Opinion in Urology·Ekaterina LaukhtinaShahrokh F Shariat

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