Comorbidities Are Associated with Altered Health Services Use in Multiple Sclerosis: A Prospective Cohort Study

Neuroepidemiology
K A McKayH Tremlett

Abstract

Persons with multiple sclerosis (MS) use health resources with greater frequency than the general population. However, little is known regarding which patient characteristics might contribute. The study aimed to evaluate characteristics associated with healthcare use in MS patients. Consecutive MS clinic attendees were recruited (September-November 2010), with clinical, demographic, and patient-completed questionnaires collected at 3 visits over 2 years. Linkage with administrative data (hospital, physician, and pharmacy records) provided healthcare use outcomes until December 31, 2013. Findings were reported as adjusted rate ratios (adjRRs) using negative binomial regression. A total of 340 MS patients with a mean (SD) age of 48.4 (12.0) years and subsequent follow-up of 3.1 (0.34) years were included. Fatigue and high physical comorbidity count (≥3 vs. none) were significantly associated with higher rates of physician encounters (adjRRs: 1.37 and 1.52, respectively), prescriptions filled (adjRRs: 1.25 and 1.40), and hospitalizations (adjRRs: 4.02 and 3.45). In addition, anxiety, disruptive pain, and perceived functional cognitive difficulties were associated with higher rates of physician encounters and prescriptions dispense...Continue Reading

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Citations

May 28, 2020·Multiple Sclerosis : Clinical and Laboratory Research·Xavier AyrignacPierre Duquette
Sep 26, 2020·Frontiers in Neurology·Melinda Magyari, Per Soelberg Sorensen
Oct 14, 2020·Multiple Sclerosis : Clinical and Laboratory Research·Ruth Ann MarrieUNKNOWN CIHR Team in Defining the Burden and Managing the Effects of Psychiatric Comorbidity in Chronic Immunoinflammatory Disease
Jul 4, 2020·Multiple Sclerosis and Related Disorders·Anna-Leena PirttisaloMerja Soilu-Hänninen
Mar 16, 2021·Multiple Sclerosis : Clinical and Laboratory Research·Kathleen M ZackowskiAnthony Feinstein
May 29, 2021·Multiple Sclerosis : Clinical and Laboratory Research·Jonathan RouxUNKNOWN BeAMS Study group
Jul 23, 2021·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·Simón Cárdenas-RobledoMar Tintoré

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