Comorbidities in pediatric alopecia areata

Journal of the European Academy of Dermatology and Venereology : JEADV
Ruzica Z ConicWilma Bergfeld

Abstract

Comorbidities are associated with higher health care costs, complex management, and poorer health outcomes. Identification and treatment of comorbid conditions in paediatric alopecia areata (AA) patients could provide an opportunity to improve health outcomes. To determine the prevalence of comorbidities among paediatric patients with AA using a large de-identified aggregated patient database. This is a cross-sectional study using aggregated health record data through April 1, 2019. Patients ≤18 years of age, with alopecia areata (n = 3510) and without alopecia areata (n = 8 310 710) were identified. The primary outcome was the prevalence of comorbidities among AA patients. Of the 8 314 220 paediatric patients, 3510 (1570 males and 1940 females) had a diagnosis of alopecia areata. The most common comorbidities included atopic dermatitis (17.4% vs. 2.2% controls, OR 9.2, 95% CI 8.55-10.18, P < 0.001), anaemia (7.7% vs. 2.4% controls, OR 3.4, 95% CI 3.06-3.92, P < 0.001), obesity (5.7% vs. 1.1% controls, OR 5.6, 95% CI 4.76-6.34, P < 0.001), vitamin D deficiency (5.1% vs. 0.4% controls, OR 14.7, 95% CI 13.5-18.1, P < 0.001), hypothyroidism (2.6% vs. 0.2% controls, OR 12, 95% CI 10.73-15.9, P < 0.001), vitiligo (1.4% vs. 0.04% con...Continue Reading

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Citations

Oct 14, 2020·International Journal of Immunopathology and Pharmacology·Yang-Chun XuPing Li
Sep 13, 2020·Journal of the European Academy of Dermatology and Venereology : JEADV·L Rudnicka, A Waśkiel-Burnat
Aug 31, 2021·Postgraduate Medicine·Piyu Parth Naik, Syed Nadir Farrukh

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