Comorbidity and prognostic factors on admission in a COVID-19 cohort of a general hospital.

Revista clínica española
F Martos PérezM V Núñez Rodríguez

Abstract

To describe clinical features, comorbidity, and prognostic factors associated with in-hospital mortality in a cohort of COVID-19 admitted to a general hospital. Retrospective cohort study of patients with COVID-19 admitted from 26th February, who had been discharged or died, up to 29th April, 2020. A descriptive study and an analysis of factors associated with intrahospital mortality were performed. Out of the 101 patients, 96 were analysed. Of these, 79 (82%) recovered and were discharged, and 17 (18%) died in the hospital. Diagnosis of COVID-19 was confirmed by polymerase chain reaction to SARS-CoV-2 in 92 (92.5%). The mean age was 63 years, and 66% were male. The most frequent comorbidities were hypertension (40%), diabetes mellitus (16%) and cardiopathy (14%). Patients who died were older (mean 77 vs 60 years), had higher prevalence of hypertension (71% vs 33%), and cardiopathy (47% vs 6%), and higher levels of lactate dehydrogenase (LDH) and reactive C protein (mean 662 vs 335UI/L, and 193 vs 121mg/L respectively) on admission. In a multivariant analysis the variables significantly associated to mortality were the presence of cardiopathy (CI 95% OR 2,58-67,07), levels of LDH≥345IU/L (CI 95% OR 1,52-46,00), and age≥65 years...Continue Reading

References

Feb 8, 2020·JAMA : the Journal of the American Medical Association·Dawei WangZhiyong Peng
Apr 7, 2020·JAMA : the Journal of the American Medical Association·Giacomo GrasselliUNKNOWN COVID-19 Lombardy ICU Network
Apr 9, 2020·BMJ : British Medical Journal·Laure WynantsMaarten van Smeden
Apr 10, 2020·The European Respiratory Journal·Rong-Hui DuHuan-Zhong Shi
Apr 25, 2020·JAMA : the Journal of the American Medical Association·Laura C MyersVincent X Liu
May 8, 2020·MMWR. Morbidity and Mortality Weekly Report·Jeremy A W GoldBrendan R Jackson

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Citations

May 29, 2021·Scientific Reports·Daniel Morell-GarciaAna García-Raja
Oct 13, 2021·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Marta Mesalles-RuizXavier Gonzàlez-Compta

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Methods Mentioned

BETA
PCR

Software Mentioned

SPSS

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