Abstract
The purpose of this study was to examine the proportion of men who died from prostate cancer (PrCa) vs. with PrCa and assess the comorbid conditions associated with other-cause deaths. We identified all male decedents aged >/=65 years in Jefferson County, AL, in 1993-1995. By crosslinking three databases (death certificate, Medicare, and Veteran's Administration), we identified men whose deaths might have been caused by PrCa. We abstracted and reviewed medical records to rate comorbid conditions and determine whether or not death was due to PrCa. Of 561 men with a premortem diagnosis of PrCa, 42% died from PrCa and 53% died with PrCA; 50.2% of blacks died from PrCa vs. 36.9% of Whites. Other factors related to dying with PrCa included older age at death and a serious, or very serious, comorbid condition. Treatment did not have an independent effect on cause of death (i.e., death with vs. from PrCa). Comorbidity was an independent predictor of dying with PrCa, even after adjustment for ethnicity, age, and treatment. Given the as yet unproven benefit of PrCa screening, our results extend the body of information relevant to the screening decision; among men dying with a diagnosis of PrCa, only about 1/3 to 1/2 died from the disease.
References
Oct 15, 1992·Cancer·A P Polednak, J T Flannery
Aug 1, 1995·The Journal of Urology·G AusL Norlén
Aug 23, 1995·JAMA : the Journal of the American Medical Association·P C AlbertsenJ Fine
Nov 1, 1993·Annals of Internal Medicine·B S KramerJ K Gohagan
Feb 1, 1993·Medical Care·S GreenfieldP D Cleary
May 26, 1993·JAMA : the Journal of the American Medical Association·G L Lu-YaoJ E Wennberg
Jul 1, 1996·The Journal of Urology·P C AlbertsenJ Fine
Nov 1, 1995·Environmental Health Perspectives·B WalkerS H Zahm
Nov 1, 1996·The Journal of Urology·J E FowlerD L Renfroe
Dec 4, 1996·JAMA : the Journal of the American Medical Association·D G FrybackB E Storer
Aug 15, 1998·Clinical Oncology : a Journal of the Royal College of Radiologists·T J Wilt
Sep 18, 1998·Cancer·W A SatarianoS K Van Den Eeden
Jun 24, 1999·Journal of the National Cancer Institute·B F HankeyR S Kaplan
Apr 20, 2000·Journal of the National Cancer Institute·C J NewschafferL T Penberthy
Jan 5, 2002·International Journal of Cancer. Journal International Du Cancer·Harry J de KoningUNKNOWN International Prostate Cancer Screening Trials Evaluation Group
Sep 13, 2002·The New England Journal of Medicine·Lars HolmbergUNKNOWN Scandinavian Prostatic Cancer Group Study Number 4
Dec 31, 2002·The American Journal of Medicine·David F RansohoffFloyd J Fowler
Citations
Feb 20, 2010·Cancer Causes & Control : CCC·Dong Wook ShinYoung Ho Yun
Sep 18, 2009·Journal of Cancer Survivorship : Research and Practice·Gregory P BeehlerLaura O Wray
Feb 28, 2014·BMJ : British Medical Journal·Prasanna SooriakumaranPeter Wiklund
Apr 10, 2009·Medical Care Research and Review : MCRR·Mary PuttKatrina Armstrong
Mar 16, 2007·Chest·Yu-Chun WangFung-Chang Sung
Feb 8, 2011·European Urology·Charles B Simone, Charles B Simone
Jul 1, 2010·Obesity Research & Clinical Practice·Gregory P BeehlerLaura O Wray
Jan 2, 2010·Archives of Gerontology and Geriatrics·F FioricaF Cartei
Nov 26, 2008·Seminars in Oncology·Supriya G MohileWilliam Dale
Mar 18, 2008·The Journal of Urology·Badrinath R KonetyUNKNOWN CaPSURE Investigators
Sep 22, 2007·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·S A M van de SchansJ W W Coebergh
May 1, 2007·European Urology·Jan AdolfssonSeymour Levitt
Aug 23, 2011·Cancer·Patti A GroomeWilliam J Mackillop
Feb 23, 2011·Journal of the American Dietetic Association·Kim RobienCheryl L Rock
Mar 24, 2016·Nature Reviews. Urology·Sarathi KalraJeri Kim
Aug 22, 2009·Cancer radiothérapie : journal de la Société française de radiothérapie oncologique·T D NguyenR C Miller
Aug 28, 2016·Contemporary Clinical Trials·Mallory G CasesWendy Demark-Wahnefried
Sep 1, 2006·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Suzie J OttoHarry J de Koning
May 7, 2016·Tumori·Giovenzio GenestretiAlba A Brandes
Feb 22, 2012·Gerontology·Amanda Black, Christine D Berg
May 23, 2007·Cancer·Charles J RyanPeter R Carroll
Mar 18, 2006·Cancer·Jun KawakamiUNKNOWN CaPSURE Investigators
Dec 31, 2004·Family & Community Health·Claudia M HardyFreddie White-Johnson
Nov 11, 2018·Nature Reviews. Clinical Oncology·Lisa M LowensteinJeri Kim
Jul 9, 2008·Scandinavian Journal of Urology and Nephrology·Katja FallUNKNOWN South-East Region Prostate Cancer Group
Mar 15, 2019·Medicina·Simona Di FrancescoElena Toniato