Comorbidity is more common and occurs earlier in persons living with HIV than in HIV-uninfected matched controls, aged 50 years and older: A cross-sectional study

International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases
Rafael Aguiar MacielEduardo Sprinz

Abstract

At present, data are limited on the comorbidity profiles associated with aging people with HIV in the developing world, where most such people live. The aim of this study was to compare the disease burden between older HIV-positive subjects and HIV-negative matched controls in Brazil. This was a cross-sectional analysis of the South Brazilian HIV Cohort. Individuals aged 50 years and older were enrolled at Hospital de Clínicas de Porto Alegre and matched with HIV-negative controls from the primary practice unit of the same hospital. Multimorbidity (the presence of two or more comorbid conditions) and the number of non-infectious comorbidities were compared. Poisson regression was used to identify factors associated with multimorbidity. A total of 208 HIV-positive subjects were matched to 208 HIV-negative controls. Overall, the median age was 57 years and 56% were male. The prevalence of multimorbidity was higher in HIV-positive subjects than in HIV-negative controls (63% vs. 43%, p<0.001), and the median number of comorbidities was 2, compared to 1 in controls (p<0.001). The duration of HIV infection (p=0.02) and time on treatment in years (p=0.015) were associated with greater multimorbidity in HIV-positive persons. In this la...Continue Reading

Citations

Mar 27, 2019·The Nurse Practitioner·Jeffrey KwongThomas J Loveless
Dec 10, 2019·Current Opinion in HIV and AIDS·Mary C Masters, Kristine M Erlandson
Nov 15, 2019·The Journal of the Association of Nurses in AIDS Care : JANAC·Nadia WinstonLisa L Barnes
Aug 14, 2020·African Journal of Primary Health Care & Family Medicine·Laston GonahKhumbulani Hlongwana
Nov 13, 2019·AIDS Research and Human Retroviruses·Abimbola Margaret ObimakindeDavid Olaleye
Jul 2, 2019·AIDS·Davide De FrancescoUNKNOWN Pharmacokinetic and Clinical Observations in PeoPle Over fiftY (POPPY) study
Sep 26, 2019·Frontiers in Immunology·Geetha MylvaganamBruce D Walker
Mar 29, 2020·Journal of Gerontological Nursing·Judy Frain
Jan 31, 2020·Current Opinion in HIV and AIDS·Mary C Masters, Kristine M Erlandson
Sep 5, 2019·Journal of the International Association of Providers of AIDS Care·Erica R M PoolHelen Smith
Jun 20, 2020·PloS One·Pablo F Belaunzaran-ZamudioUNKNOWN Caribbean, Central and South American network for HIV epidemiology (CCASAnet)
Feb 6, 2020·Journal of the International AIDS Society·David Back, Catia Marzolini
May 10, 2019·Frontiers in Public Health·Sherry DerenBei Wu
Jul 28, 2020·International Journal of Environmental Research and Public Health·Philipp ZechAndreas Heissel
Jun 27, 2019·BMC Infectious Diseases·Paolo MaggiGiuseppe Vittorio De Socio
Jan 6, 2021·Current HIV/AIDS Reports·Diego M CabreraEvelyn Hsieh
Nov 30, 2019·The Lancet. HIV·Kelly Safreed-HarmonJeffrey V Lazarus
Dec 19, 2020·HIV/AIDS : Research and Palliative Care·Abdulnaser AlgarallehFatima Al-Tarawneh
Mar 6, 2021·Journal of Clinical Pharmacy and Therapeutics·Idongesit L Jackson, Chinwe V Ukwe
Apr 5, 2021·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·Ioana D OlaruKatharina Kranzer
May 20, 2021·International Journal of STD & AIDS·Hartmut B Krentz, M John Gill
Jun 3, 2021·Medicina·Opeyemi M FolorunsoOrish E Orisakwe
Jun 29, 2021·Frontiers in Psychology·Maria José Fuster-RuizdeApodacaJeffrey V Lazarus
Jul 31, 2021·The Lancet Regional Health. Western Pacific·Sithara Wanni Arachchige DonaJulie Abimanyi-Ochom
Nov 14, 2020·African Journal of Primary Health Care & Family Medicine·Laston GonahKhumbulani Hlongwana
Sep 2, 2021·HIV Medicine·Heather A Leake DateJaime H Vera
Jun 4, 2021·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Vanessa A GuzmanUNKNOWN Manhattan HIV Brain Bank
May 31, 2019·Current Opinion in Organ Transplantation·Brian J BoyarskyChristine M Durand
Oct 16, 2021·Journal of Neuroendocrinology·Mohammed F SalahuddinJason J Paris
Jan 12, 2022·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Mary C MastersFrank J Palella

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Revista brasileira de psiquiatria : orgão oficial da Associação Brasileira de Psiquiatria, Asociación Psiquiátrica de la América Latina
Aline R WageckMaurício Kunz
Menopause : the Journal of the North American Menopause Society
Vanessa de S Santos MachadoAarão Mendes Pinto-Neto
Journal of the American Society of Hypertension : JASH
Vicente Sperb AntonelloLisiane de Quadros Winckler
© 2022 Meta ULC. All rights reserved